Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | tacT-ataR/DUF1778(antitoxin) |
| Location | 19269..20026 | Replicon | plasmid 2 |
| Accession | NZ_LN890523 | ||
| Organism | Salmonella enterica subsp. enterica serovar Weltevreden strain 2511STDY5712384 | ||
Toxin (Protein)
| Gene name | tacT | Uniprot ID | A0A4U8I7M5 |
| Locus tag | ARC26_RS23600 | Protein ID | WP_000406363.1 |
| Coordinates | 19269..19751 (-) | Length | 161 a.a. |
Antitoxin (Protein)
| Gene name | ataR | Uniprot ID | A0A4U8I6Z6 |
| Locus tag | ARC26_RS23605 | Protein ID | WP_001195099.1 |
| Coordinates | 19742..20026 (-) | Length | 95 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| ARC26_RS26410 | 15188..16299 | + | 1112 | WP_106086674.1 | IS3 family transposase | - |
| ARC26_RS23580 | 16311..17069 | - | 759 | WP_000493752.1 | 4'-phosphopantetheinyl transferase superfamily protein | - |
| ARC26_RS23585 | 17227..17511 | + | 285 | WP_000537154.1 | IS3 family transposase | - |
| ARC26_RS23590 | 17508..18362 | + | 855 | WP_077905131.1 | IS3 family transposase | - |
| ARC26_RS23595 | 18436..18885 | - | 450 | WP_000750479.1 | hypothetical protein | - |
| ARC26_RS23600 | 19269..19751 | - | 483 | WP_000406363.1 | GNAT family N-acetyltransferase | Toxin |
| ARC26_RS23605 | 19742..20026 | - | 285 | WP_001195099.1 | DUF1778 domain-containing protein | Antitoxin |
| ARC26_RS23610 | 20338..20598 | + | 261 | WP_000929810.1 | hypothetical protein | - |
| ARC26_RS23615 | 20595..21557 | + | 963 | WP_000145248.1 | hypothetical protein | - |
| ARC26_RS23620 | 21542..21820 | - | 279 | WP_000534855.1 | cloacin | - |
| ARC26_RS25425 | 22157..22351 | - | 195 | Protein_12 | DUF4158 domain-containing protein | - |
| ARC26_RS23630 | 22754..23803 | - | 1050 | WP_001534988.1 | hypothetical protein | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| - | inside | Non-Mobilizable plasmid | - | - | 1..82119 | 82119 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 161 a.a. Molecular weight: 23713.45 Da Isoelectric Point: 5.5500
>T285776 WP_000406363.1 NZ_LN890523:c19751-19269 [Salmonella enterica subsp. enterica serovar Weltevreden]
FFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFF
FFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFF
F
FFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFF
FFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFF
F
Download Length: 483 bp
Antitoxin
Download Length: 95 a.a. Molecular weight: 13999.79 Da Isoelectric Point: 5.5500
>AT285776 WP_001195099.1 NZ_LN890523:c20026-19742 [Salmonella enterica subsp. enterica serovar Weltevreden]
FFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFF
FFFFFFFFFFFFFFF
FFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFF
FFFFFFFFFFFFFFF
Download Length: 285 bp
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
Structures
Toxin
| Source | ID | Structure |
|---|---|---|
| AlphaFold DB | A0A4U8I7M5 |
Antitoxin
| Source | ID | Structure |
|---|---|---|
| AlphaFold DB | A0A4U8I6Z6 |