Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | tacT-ataR/DUF1778(antitoxin) |
| Location | 63793..64550 | Replicon | plasmid 2 |
| Accession | NZ_LN890519 | ||
| Organism | Salmonella enterica subsp. enterica serovar Weltevreden strain 2511STDY5462388 | ||
Toxin (Protein)
| Gene name | tacT | Uniprot ID | A0A4U8I7M5 |
| Locus tag | ARC00_RS25055 | Protein ID | WP_000406363.1 |
| Coordinates | 64068..64550 (+) | Length | 161 a.a. |
Antitoxin (Protein)
| Gene name | ataR | Uniprot ID | A0A4U8I6Z6 |
| Locus tag | ARC00_RS25050 | Protein ID | WP_001195099.1 |
| Coordinates | 63793..64077 (+) | Length | 95 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| ARC00_RS25025 | 60016..61065 | + | 1050 | WP_001534988.1 | hypothetical protein | - |
| ARC00_RS26910 | 61468..61662 | + | 195 | Protein_73 | DUF4158 domain-containing protein | - |
| ARC00_RS25035 | 61999..62277 | + | 279 | WP_000534855.1 | cloacin | - |
| ARC00_RS25040 | 62262..63224 | - | 963 | WP_000145248.1 | hypothetical protein | - |
| ARC00_RS25045 | 63221..63481 | - | 261 | WP_000929810.1 | hypothetical protein | - |
| ARC00_RS25050 | 63793..64077 | + | 285 | WP_001195099.1 | DUF1778 domain-containing protein | Antitoxin |
| ARC00_RS25055 | 64068..64550 | + | 483 | WP_000406363.1 | GNAT family N-acetyltransferase | Toxin |
| ARC00_RS25060 | 64934..65383 | + | 450 | WP_000750479.1 | hypothetical protein | - |
| ARC00_RS25065 | 65457..66311 | - | 855 | WP_077905131.1 | IS3 family transposase | - |
| ARC00_RS25070 | 66308..66592 | - | 285 | WP_000537154.1 | IS3 family transposase | - |
| ARC00_RS25075 | 66750..67508 | + | 759 | WP_000493752.1 | 4'-phosphopantetheinyl transferase superfamily protein | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| - | inside | Non-Mobilizable plasmid | - | - | 1..98756 | 98756 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 161 a.a. Molecular weight: 20654.05 Da Isoelectric Point: 13.0041
>T285774 WP_000406363.1 NZ_LN890519:64068-64550 [Salmonella enterica subsp. enterica serovar Weltevreden]
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Download Length: 483 bp
Antitoxin
Download Length: 95 a.a. Molecular weight: 12194.55 Da Isoelectric Point: 12.7731
>AT285774 WP_001195099.1 NZ_LN890519:63793-64077 [Salmonella enterica subsp. enterica serovar Weltevreden]
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Download Length: 285 bp
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
Structures
Toxin
| Source | ID | Structure |
|---|---|---|
| AlphaFold DB | A0A4U8I7M5 |
Antitoxin
| Source | ID | Structure |
|---|---|---|
| AlphaFold DB | A0A4U8I6Z6 |