Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) hicAB/HicB(antitoxin)
Location 4172984..4173664 Replicon chromosome
Accession NZ_LN890477
Organism Achromobacter xylosoxidans isolate R8

Toxin (Protein)


Gene name hicA Uniprot ID -
Locus tag BN2910_RS19565 Protein ID WP_006386381.1
Coordinates 4172984..4173169 (+) Length 62 a.a.

Antitoxin (Protein)


Gene name hicB Uniprot ID -
Locus tag BN2910_RS19570 Protein ID WP_006386380.1
Coordinates 4173245..4173664 (+) Length 140 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
BN2910_RS19555 4169123..4170526 + 1404 WP_054446896.1 dihydrolipoyl dehydrogenase -
BN2910_RS19560 4170698..4172737 - 2040 WP_054482409.1 pyruvate, phosphate dikinase -
BN2910_RS19565 4172984..4173169 + 186 WP_006386381.1 type II toxin-antitoxin system HicA family toxin Toxin
BN2910_RS19570 4173245..4173664 + 420 WP_006386380.1 type II toxin-antitoxin system HicB family antitoxin Antitoxin
BN2910_RS19575 4173755..4175173 - 1419 WP_006386379.1 argininosuccinate lyase -
BN2910_RS19580 4175386..4176717 + 1332 WP_026382696.1 mechanosensitive ion channel -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

HicA mRNA interferase family

(3-60)

Antitoxin

HicB-like antitoxin of toxin-antitoxin system

(4-94)


Sequences

Toxin        


Download         Length: 62 a.a.        Molecular weight: 7058.16 Da        Isoelectric Point: 10.6654

>T285770 WP_006386381.1 NZ_LN890477:4172984-4173169 [Achromobacter xylosoxidans]
MKYSEFKKWLERQGAVFVAHRSGSSHFRVTLNGATTIFPYHGSKEMGKHLEHEIKKQLGLK

Download         Length: 186 bp

Antitoxin


Download         Length: 140 a.a.        Molecular weight: 15506.81 Da        Isoelectric Point: 4.9597

>AT285770 WP_006386380.1 NZ_LN890477:4173245-4173664 [Achromobacter xylosoxidans]
MLTYPFTLTLDSNRTWLVRFPDIPEALTVGDDEQEAAINAREALEAALEIYFDARRPIPLPSPVSAGQASVTLPALITSK
VFLSNEMIQQGVRKAELARRMGVHMPQVDRLLDVRHASRIEQVESALEQLGRRLEVSLA

Download         Length: 420 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References