Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RelE-RelB
Location 3432137..3432701 Replicon chromosome
Accession NZ_LN890477
Organism Achromobacter xylosoxidans isolate R8

Toxin (Protein)


Gene name relE Uniprot ID A0A0D6IHV7
Locus tag BN2910_RS16085 Protein ID WP_020926667.1
Coordinates 3432420..3432701 (+) Length 94 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID A0A0D6IHW1
Locus tag BN2910_RS16080 Protein ID WP_020926666.1
Coordinates 3432137..3432433 (+) Length 99 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
BN2910_RS16055 3427591..3427902 - 312 WP_006386651.1 helix-turn-helix domain-containing protein -
BN2910_RS16060 3427899..3428267 - 369 WP_006386650.1 type II toxin-antitoxin system RelE/ParE family toxin -
BN2910_RS16065 3428437..3429372 - 936 WP_006386649.1 protein translocase subunit SecF -
BN2910_RS16070 3429424..3431304 - 1881 WP_006386648.1 protein translocase subunit SecD -
BN2910_RS16075 3431420..3431764 - 345 WP_006386647.1 preprotein translocase subunit YajC -
BN2910_RS16080 3432137..3432433 + 297 WP_020926666.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
BN2910_RS16085 3432420..3432701 + 282 WP_020926667.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
BN2910_RS16090 3432751..3433887 - 1137 WP_020926668.1 tRNA guanosine(34) transglycosylase Tgt -
BN2910_RS16095 3433884..3434939 - 1056 WP_026385110.1 tRNA preQ1(34) S-adenosylmethionine ribosyltransferase-isomerase QueA -
BN2910_RS16100 3435175..3436008 - 834 WP_155872454.1 IclR family transcriptional regulator -
BN2910_RS16105 3436130..3437143 + 1014 WP_155872455.1 LLM class flavin-dependent oxidoreductase -
BN2910_RS16110 3437167..3437670 + 504 WP_047993287.1 flavin reductase family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-90)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(4-52)


Sequences

Toxin        


Download         Length: 94 a.a.        Molecular weight: 10262.77 Da        Isoelectric Point: 7.0080

>T285769 WP_020926667.1 NZ_LN890477:3432420-3432701 [Achromobacter xylosoxidans]
VPAVEWSSAARADLLAIVDYISDDNPDAAQRLKDDIETKAAQLPARPALYRPGRIAGTREMVVRANYIIVYAADALAVRI
LRILHAAQQWPPQ

Download         Length: 282 bp

Antitoxin


Download         Length: 99 a.a.        Molecular weight: 10717.24 Da        Isoelectric Point: 7.3208

>AT285769 WP_020926666.1 NZ_LN890477:3432137-3432433 [Achromobacter xylosoxidans]
MPQTSMLHVRVDDKLKADATEKLAEFGLTISDAVRILLTRVAKEGGLPAGLTTDAQAHDAWFRAKVQEALADTGPAVPHQ
QVMDEAQALIDRKRRARS

Download         Length: 297 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A0D6IHV7

Antitoxin

Source ID Structure
AlphaFold DB A0A0D6IHW1

References