Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-VapB
Location 1011734..1012307 Replicon chromosome
Accession NZ_LN890477
Organism Achromobacter xylosoxidans isolate R8

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag BN2910_RS04775 Protein ID WP_054507022.1
Coordinates 1011734..1012111 (-) Length 126 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag BN2910_RS04780 Protein ID WP_054471260.1
Coordinates 1012098..1012307 (-) Length 70 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
BN2910_RS04750 1008406..1009323 + 918 WP_054439442.1 septum site-determining protein MinC -
BN2910_RS04755 1009512..1010327 + 816 WP_006388978.1 septum site-determining protein MinD -
BN2910_RS04760 1010331..1010588 + 258 WP_006388977.1 cell division topological specificity factor MinE -
BN2910_RS04765 1010718..1010942 - 225 WP_006388976.1 glycine zipper 2TM domain-containing protein -
BN2910_RS04770 1011133..1011666 - 534 WP_054504957.1 isochorismatase family protein -
BN2910_RS04775 1011734..1012111 - 378 WP_054507022.1 type II toxin-antitoxin system VapC family toxin Toxin
BN2910_RS04780 1012098..1012307 - 210 WP_054471260.1 type II toxin-antitoxin system VapB family antitoxin Antitoxin
BN2910_RS04785 1012432..1014105 - 1674 WP_024067854.1 energy-dependent translational throttle protein EttA -
BN2910_RS04790 1014257..1015075 + 819 WP_054472847.1 AAC(3) family N-acetyltransferase -
BN2910_RS04795 1015088..1016014 - 927 WP_020924995.1 DMT family transporter -
BN2910_RS04800 1016113..1016901 + 789 WP_024067852.1 helix-turn-helix transcriptional regulator -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Bacterial antitoxin of type II TA system, VapB

(2-44)


Sequences

Toxin        


Download         Length: 126 a.a.        Molecular weight: 13890.15 Da        Isoelectric Point: 6.3739

>T285767 WP_054507022.1 NZ_LN890477:c1012111-1011734 [Achromobacter xylosoxidans]
MILVDTSIWIDHLSDGEPFLVRLLEEESVLMHPFIAGELALGSLGRRDVVLGAMSLLPQVVRASHDEVMHFLHSERLFGK
GIGYVDLHLLASTRLTPGAALWTRDKRLQALATTLSLAVDPPRYH

Download         Length: 378 bp

Antitoxin


Download         Length: 70 a.a.        Molecular weight: 7521.62 Da        Isoelectric Point: 9.9435

>AT285767 WP_054471260.1 NZ_LN890477:c1012307-1012098 [Achromobacter xylosoxidans]
VRTTVTLDDDLLELARTYTGVQETSALVTRALTQLVQKEAAKRLAKLGGSSPKLKPIPRRQTETCNDPG

Download         Length: 210 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References