Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/upstrm_HI1419-dnstrm_HI1420
Location 4223845..4224467 Replicon chromosome
Accession NZ_LN890476
Organism Achromobacter xylosoxidans isolate R4

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag BN2905_RS19790 Protein ID WP_054505594.1
Coordinates 4224153..4224467 (-) Length 105 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag BN2905_RS19785 Protein ID WP_054508121.1
Coordinates 4223845..4224156 (-) Length 104 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
BN2905_RS19750 4219119..4220012 + 894 WP_104414222.1 diiron oxygenase -
BN2905_RS19755 4220027..4220983 + 957 WP_155868353.1 nitronate monooxygenase -
BN2905_RS19760 4221041..4221826 + 786 WP_006386406.1 hypothetical protein -
BN2905_RS19765 4221827..4222210 + 384 WP_006386405.1 hypothetical protein -
BN2905_RS19770 4222185..4222703 + 519 WP_006386404.1 4'-phosphopantetheinyl transferase superfamily protein -
BN2905_RS19780 4222966..4223748 - 783 WP_155868354.1 exodeoxyribonuclease III -
BN2905_RS19785 4223845..4224156 - 312 WP_054508121.1 putative addiction module antidote protein Antitoxin
BN2905_RS19790 4224153..4224467 - 315 WP_054505594.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
BN2905_RS19795 4224890..4228231 + 3342 WP_155868355.1 viral (Super1) RNA helicase -
BN2905_RS19800 4228260..4229036 - 777 WP_024068578.1 3-oxoacyl-ACP reductase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Addiction module killer protein, predicted

(1-96)

Antitoxin

Cro/C1-type helix-turn-helix domain

(51-95)


Sequences

Toxin        


Download         Length: 105 a.a.        Molecular weight: 11792.46 Da        Isoelectric Point: 8.5141

>T285765 WP_054505594.1 NZ_LN890476:c4224467-4224153 [Achromobacter xylosoxidans]
MYHIKPLPEFDAWFDTLTDPATRARLIRRLEKAARGLLGDVKPVGEGVSEMREFFGPGWRMYYAERGNVLIVMLGGGTKG
TQSRDVKHAKELARALRNDEEDQS

Download         Length: 315 bp

Antitoxin


Download         Length: 104 a.a.        Molecular weight: 11104.80 Da        Isoelectric Point: 8.9514

>AT285765 WP_054508121.1 NZ_LN890476:c4224156-4223845 [Achromobacter xylosoxidans]
MSKKAIKISELPTFDPARYLRDDKDIAAYLTQVIEDGDFGELAQALGVAARARGMTQIAETTGIGRESLYKALRAGASPR
FDTIAKVCKALGVRLVVQAEHPA

Download         Length: 312 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References