Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-VapB
Location 989485..990058 Replicon chromosome
Accession NZ_LN890476
Organism Achromobacter xylosoxidans isolate R4

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag BN2905_RS04630 Protein ID WP_049054629.1
Coordinates 989485..989862 (-) Length 126 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag BN2905_RS04635 Protein ID WP_054471260.1
Coordinates 989849..990058 (-) Length 70 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
BN2905_RS04605 986157..987074 + 918 WP_054443171.1 septum site-determining protein MinC -
BN2905_RS04610 987263..988078 + 816 WP_006388978.1 septum site-determining protein MinD -
BN2905_RS04615 988082..988339 + 258 WP_006388977.1 cell division topological specificity factor MinE -
BN2905_RS04620 988469..988693 - 225 WP_006388976.1 glycine zipper 2TM domain-containing protein -
BN2905_RS04625 988884..989417 - 534 WP_024067855.1 isochorismatase family protein -
BN2905_RS04630 989485..989862 - 378 WP_049054629.1 type II toxin-antitoxin system VapC family toxin Toxin
BN2905_RS04635 989849..990058 - 210 WP_054471260.1 type II toxin-antitoxin system VapB family antitoxin Antitoxin
BN2905_RS04640 990183..991856 - 1674 WP_024067854.1 energy-dependent translational throttle protein EttA -
BN2905_RS04645 992008..992826 + 819 WP_155866994.1 AAC(3) family N-acetyltransferase -
BN2905_RS04650 992839..993765 - 927 WP_020924995.1 DMT family transporter -
BN2905_RS04655 993864..994652 + 789 WP_049054627.1 helix-turn-helix transcriptional regulator -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Bacterial antitoxin of type II TA system, VapB

(2-44)


Sequences

Toxin        


Download         Length: 126 a.a.        Molecular weight: 13846.11 Da        Isoelectric Point: 6.3721

>T285764 WP_049054629.1 NZ_LN890476:c989862-989485 [Achromobacter xylosoxidans]
MILVDTSIWIDHLSDGEPCLVRLLEEESVLMHPFIAGELALGSLGRRDVVLGAMSLLPQVVRASHDEVMHFLHSERLFGK
GIGYVDLHLLASTRLTPGAALWTRDKRLQALATTLSLAVDPPRYH

Download         Length: 378 bp

Antitoxin


Download         Length: 70 a.a.        Molecular weight: 7521.62 Da        Isoelectric Point: 9.9435

>AT285764 WP_054471260.1 NZ_LN890476:c990058-989849 [Achromobacter xylosoxidans]
VRTTVTLDDDLLELARTYTGVQETSALVTRALTQLVQKEAAKRLAKLGGSSPKLKPIPRRQTETCNDPG

Download         Length: 210 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References