Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) hicAB/HicB(antitoxin)
Location 4060329..4061009 Replicon chromosome
Accession NZ_LN890335
Organism Achromobacter xylosoxidans isolate AX_NCIMB_11015_WG

Toxin (Protein)


Gene name hicA Uniprot ID -
Locus tag BN2877_RS18670 Protein ID WP_006386381.1
Coordinates 4060329..4060514 (+) Length 62 a.a.

Antitoxin (Protein)


Gene name hicB Uniprot ID -
Locus tag BN2877_RS18675 Protein ID WP_006386380.1
Coordinates 4060590..4061009 (+) Length 140 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
BN2877_RS18660 4056465..4057868 + 1404 WP_107316537.1 dihydrolipoyl dehydrogenase -
BN2877_RS18665 4058043..4060081 - 2039 Protein_3673 pyruvate, phosphate dikinase -
BN2877_RS18670 4060329..4060514 + 186 WP_006386381.1 type II toxin-antitoxin system HicA family toxin Toxin
BN2877_RS18675 4060590..4061009 + 420 WP_006386380.1 type II toxin-antitoxin system HicB family antitoxin Antitoxin
BN2877_RS18680 4061100..4062518 - 1419 WP_006386379.1 argininosuccinate lyase -
BN2877_RS18685 4062731..4064062 + 1332 WP_024068593.1 mechanosensitive ion channel -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

HicA mRNA interferase family

(3-60)

Antitoxin

HicB-like antitoxin of toxin-antitoxin system

(4-94)


Sequences

Toxin        


Download         Length: 62 a.a.        Molecular weight: 7058.16 Da        Isoelectric Point: 10.6654

>T285762 WP_006386381.1 NZ_LN890335:4060329-4060514 [Achromobacter xylosoxidans]
MKYSEFKKWLERQGAVFVAHRSGSSHFRVTLNGATTIFPYHGSKEMGKHLEHEIKKQLGLK

Download         Length: 186 bp

Antitoxin


Download         Length: 140 a.a.        Molecular weight: 15506.81 Da        Isoelectric Point: 4.9597

>AT285762 WP_006386380.1 NZ_LN890335:4060590-4061009 [Achromobacter xylosoxidans]
MLTYPFTLTLDSNRTWLVRFPDIPEALTVGDDEQEAAINAREALEAALEIYFDARRPIPLPSPVSAGQASVTLPALITSK
VFLSNEMIQQGVRKAELARRMGVHMPQVDRLLDVRHASRIEQVESALEQLGRRLEVSLA

Download         Length: 420 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References