Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-VapB
Location 864627..865200 Replicon chromosome
Accession NZ_LN890335
Organism Achromobacter xylosoxidans isolate AX_NCIMB_11015_WG

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag BN2877_RS03925 Protein ID WP_155864787.1
Coordinates 864627..865004 (-) Length 126 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag BN2877_RS03930 Protein ID WP_054471260.1
Coordinates 864991..865200 (-) Length 70 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
BN2877_RS03900 861299..862216 + 918 WP_054443171.1 septum site-determining protein MinC -
BN2877_RS03905 862405..863220 + 816 WP_006388978.1 septum site-determining protein MinD -
BN2877_RS03910 863224..863481 + 258 WP_006388977.1 cell division topological specificity factor MinE -
BN2877_RS03915 863611..863835 - 225 WP_006388976.1 glycine zipper 2TM domain-containing protein -
BN2877_RS03920 864026..864559 - 534 WP_054516683.1 isochorismatase family protein -
BN2877_RS03925 864627..865004 - 378 WP_155864787.1 VapC toxin family PIN domain ribonuclease Toxin
BN2877_RS03930 864991..865200 - 210 WP_054471260.1 type II toxin-antitoxin system VapB family antitoxin Antitoxin
BN2877_RS03935 865325..866998 - 1674 WP_006388972.1 energy-dependent translational throttle protein EttA -
BN2877_RS03940 867150..867968 + 819 WP_020924994.1 AAC(3) family N-acetyltransferase -
BN2877_RS03945 867981..868907 - 927 WP_020924995.1 DMT family transporter -
BN2877_RS03950 869006..869794 + 789 WP_006388969.1 helix-turn-helix transcriptional regulator -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Bacterial antitoxin of type II TA system, VapB

(2-44)


Sequences

Toxin        


Download         Length: 126 a.a.        Molecular weight: 13875.14 Da        Isoelectric Point: 6.6053

>T285758 WP_155864787.1 NZ_LN890335:c865004-864627 [Achromobacter xylosoxidans]
MILVDTSIWINHLSDGEPYLVRLLEEESVLMHPFIAGELALGSLGRRDVVLGAMSLLPQVVRASHDEVMHFLHSERLFGK
GIGYVDLHLLASTRLTPGAALWTRDKRLQALATTLGLAVDPPRYH

Download         Length: 378 bp

Antitoxin


Download         Length: 70 a.a.        Molecular weight: 7521.62 Da        Isoelectric Point: 9.9435

>AT285758 WP_054471260.1 NZ_LN890335:c865200-864991 [Achromobacter xylosoxidans]
VRTTVTLDDDLLELARTYTGVQETSALVTRALTQLVQKEAAKRLAKLGGSSPKLKPIPRRQTETCNDPG

Download         Length: 210 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References