Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) phd-doc/HTH_IclR(antitoxin)
Location 4894543..4896233 Replicon chromosome
Accession NZ_LN879547
Organism Comamonas thiooxydans isolate C19

Toxin (Protein)


Gene name doc Uniprot ID -
Locus tag BN2297_RS22265 Protein ID WP_057094001.1
Coordinates 4895355..4896233 (-) Length 293 a.a.

Antitoxin (Protein)


Gene name phd Uniprot ID -
Locus tag BN2297_RS22260 Protein ID WP_057093999.1
Coordinates 4894543..4895349 (-) Length 269 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Alpha/beta hydrolase fold-1

(44-277)

Antitoxin

Transcription regulator IclR, C-terminal

(137-257)


Sequences

Toxin        


Download         Length: 293 a.a.        Molecular weight: 30598.03 Da        Isoelectric Point: 6.0748

>T285752 WP_057094001.1 NZ_LN879547:c4896233-4895355 [Comamonas thiooxydans]
MHEDLLSLKLQLLQTGFPERLVKLPQDAQVAWREAGDASSDFAVVLLHGISSGAASWLDVALQLADKVRVLAWDAPGYGV
STPLAQSAPADADYAHALAQSLLVLGVRRCILVGHSLGALMAARLAVTAAPGLVEQLVLISPAGGYGAAAKAEQQAKVRE
GRLAALADKGVAGLAAVIDQRLVSSEAPEAVRAWVRWNTARMQPQGYAQAVELLCGSDLAQAQGRLGMPVEVWVGEHDVV
TTPAACKSWSELLGAHYGTLAAAGHASPVEQPMEVAHRLASLLNQSYCPNTS

Download         Length: 879 bp

Antitoxin


Download         Length: 269 a.a.        Molecular weight: 29285.26 Da        Isoelectric Point: 5.1709

>AT285752 WP_057093999.1 NZ_LN879547:c4895349-4894543 [Comamonas thiooxydans]
MSETPEISTNEQDRYTVPALDRGLRLLACFGPTQPVWSAPELARKLELPRSTVFRMLTTLENSGYLQRSGTEYRLGLAVL
RLGYDYLSTQPLAQLAEPVLQALCDELGMTSNLALRDGTSVVYVARVTPSGAFQGAVRVGSRLPAHATVLGRALLHDMDG
AQLRSVFGGEELPQFSESTPRNVDELLRLLAEDRERGYAMGEGFYEPGVSSIAAPVRAADGQVVAGLGMAIPFTELGPEK
TQLWVQKVQEAAETLSAHLRQQHPDHLR

Download         Length: 807 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References