Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | /Xre(antitoxin) |
Location | 4398455..4399713 | Replicon | chromosome |
Accession | NZ_LN871187 | ||
Organism | Pseudomonas aeruginosa strain PAO1_Orsay |
Toxin (Protein)
Gene name | - | Uniprot ID | Q9I4U4 |
Locus tag | PAO1OR_RS20170 | Protein ID | WP_003112528.1 |
Coordinates | 4398455..4399210 (-) | Length | 252 a.a. |
Antitoxin (Protein)
Gene name | - | Uniprot ID | V6AJU7 |
Locus tag | PAO1OR_RS20175 | Protein ID | WP_003086329.1 |
Coordinates | 4399345..4399713 (-) | Length | 123 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
PAO1OR_RS20160 | 4393628..4396171 | + | 2544 | WP_003112526.1 | acyl-homoserine-lactone acylase QuiP | - |
PAO1OR_RS20165 | 4396326..4397687 | - | 1362 | WP_010895536.1 | DNA recombination protein RmuC | - |
PAO1OR_RS20170 | 4398455..4399210 | - | 756 | WP_003112528.1 | RES family NAD+ phosphorylase | Toxin |
PAO1OR_RS20175 | 4399345..4399713 | - | 369 | WP_003086329.1 | DUF2384 domain-containing protein | Antitoxin |
PAO1OR_RS20180 | 4399786..4401072 | - | 1287 | WP_003112529.1 | FAD-binding oxidoreductase | - |
PAO1OR_RS20185 | 4401128..4402717 | - | 1590 | WP_010895535.1 | aldehyde dehydrogenase family protein | - |
PAO1OR_RS20190 | 4402796..4403272 | + | 477 | WP_003112531.1 | hypothetical protein | - |
PAO1OR_RS29970 | 4403275..4403550 | - | 276 | WP_010793902.1 | zinc ribbon domain-containing protein | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
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Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 252 a.a. Molecular weight: 28278.42 Da Isoelectric Point: 7.7294
>T285739 WP_003112528.1 NZ_LN871187:c4399210-4398455 [Pseudomonas aeruginosa]
VSEIWRQCKGERHIRPLQGRLVRLVESQEQVATLQLVDTLEEQALLEELLESSKPPVPADAEPLHYLLKTPFRYPPLRWG
SRFGRRHEPSLFYAALKLETAMAESAYYRCVLWSGMVVPPPSGRILSEHASFEAGWKVERGIRLQAPPFSDHEAALTDIA
DYRAPQELGSAMRSAGVQAFEYRSARCPERGCNVALFTPAAFTEKRPRNLTPWLCETTAGYVAFKPAHVPGSPKIFSWEL
FLVDGKLPHPA
VSEIWRQCKGERHIRPLQGRLVRLVESQEQVATLQLVDTLEEQALLEELLESSKPPVPADAEPLHYLLKTPFRYPPLRWG
SRFGRRHEPSLFYAALKLETAMAESAYYRCVLWSGMVVPPPSGRILSEHASFEAGWKVERGIRLQAPPFSDHEAALTDIA
DYRAPQELGSAMRSAGVQAFEYRSARCPERGCNVALFTPAAFTEKRPRNLTPWLCETTAGYVAFKPAHVPGSPKIFSWEL
FLVDGKLPHPA
Download Length: 756 bp
Antitoxin
Download Length: 123 a.a. Molecular weight: 13367.63 Da Isoelectric Point: 9.9874
>AT285739 WP_003086329.1 NZ_LN871187:c4399713-4399345 [Pseudomonas aeruginosa]
MSALIKERPSADAVLAKAVLAAREQLGLTQLELAGIVGVDRSAISRWKTQGLRVDSKTGELALLLVRVYRALYALFGGQQ
EDMRHFLRTPNHHLAGEPLALMGQVQGLVHVLEYLDAIRGKV
MSALIKERPSADAVLAKAVLAAREQLGLTQLELAGIVGVDRSAISRWKTQGLRVDSKTGELALLLVRVYRALYALFGGQQ
EDMRHFLRTPNHHLAGEPLALMGQVQGLVHVLEYLDAIRGKV
Download Length: 369 bp
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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