Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/-
Location 479120..479773 Replicon chromosome
Accession NZ_LN868200
Organism Acinetobacter baumannii isolate R2090

Toxin (Protein)


Gene name cptA Uniprot ID -
Locus tag ABR2090_RS02350 Protein ID WP_000607097.1
Coordinates 479384..479773 (+) Length 130 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID V5V966
Locus tag ABR2090_RS02345 Protein ID WP_001288210.1
Coordinates 479120..479377 (+) Length 86 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
ABR2090_RS02325 474635..475642 + 1008 WP_000198631.1 DNA-directed RNA polymerase subunit alpha -
ABR2090_RS02330 475661..476038 + 378 WP_001216380.1 50S ribosomal protein L17 -
ABR2090_RS02335 476220..477710 + 1491 WP_000415133.1 NAD(P)/FAD-dependent oxidoreductase -
ABR2090_RS02340 477760..478932 - 1173 WP_001190546.1 acyl-CoA dehydrogenase family protein -
ABR2090_RS02345 479120..479377 + 258 WP_001288210.1 succinate dehydrogenase assembly factor 2 Antitoxin
ABR2090_RS02350 479384..479773 + 390 WP_000607097.1 hypothetical protein Toxin
ABR2090_RS02355 480543..481628 + 1086 WP_000049106.1 hypothetical protein -
ABR2090_RS02360 481706..482272 + 567 WP_000651536.1 rhombosortase -
ABR2090_RS02365 482460..484655 + 2196 WP_001158905.1 TRAP transporter large permease subunit -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Flavinator of succinate dehydrogenase

(10-82)


Sequences

Toxin        


Download         Length: 130 a.a.        Molecular weight: 15637.89 Da        Isoelectric Point: 10.3890

>T285722 WP_000607097.1 NZ_LN868200:479384-479773 [Acinetobacter baumannii]
MINHSNFKLKYSRFSIIFQFFIGLSLAVLFYQLMPLLWWLVVISLLFISFIFFLKRPQLAQIAYLDKKLWSLAYHSQNTI
SRVKILKIIDYQIFIVIYFEGHKTLTSIIWFDQMSLVEWKKLKTLEKLY

Download         Length: 390 bp

Antitoxin


Download         Length: 86 a.a.        Molecular weight: 10318.77 Da        Isoelectric Point: 4.6150

>AT285722 WP_001288210.1 NZ_LN868200:479120-479377 [Acinetobacter baumannii]
MSEEMTLEERKVIYRARRGLKEIDVYFDPYVKNYYLKADPAEKALFAELVEQEDPDLLDWFMEVSEPPRTELRDFIYKLK
HYVHG

Download         Length: 258 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB A0A7U4BQM7

References