Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-VagC
Location 2779600..2780169 Replicon chromosome
Accession NZ_LN865164
Organism Pseudomonas sp. URMO17WK12:I11 isolate Yellow

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag PSHI_RS21960 Protein ID WP_082693189.1
Coordinates 2779600..2779908 (-) Length 103 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID A0A0S4IAP2
Locus tag PSHI_RS12560 Protein ID WP_059183628.1
Coordinates 2779939..2780169 (-) Length 77 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PSHI_RS12535 2775782..2776192 + 411 WP_027915709.1 pilin -
PSHI_RS12545 2776964..2778362 + 1399 Protein_2455 PAAR domain-containing protein -
PSHI_RS12550 2778355..2778744 + 390 WP_049695408.1 hypothetical protein -
PSHI_RS12555 2778822..2779343 - 522 WP_059183627.1 cysteine hydrolase -
PSHI_RS21960 2779600..2779908 - 309 WP_082693189.1 tRNA(fMet)-specific endonuclease VapC Toxin
PSHI_RS12560 2779939..2780169 - 231 WP_059183628.1 antitoxin Antitoxin
PSHI_RS12565 2780622..2781152 + 531 WP_028688070.1 ATPase AAA -
PSHI_RS12570 2781171..2783129 - 1959 WP_059183629.1 response regulator -
PSHI_RS12575 2783341..2785116 + 1776 WP_028688071.1 sensor domain-containing phosphodiesterase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(2-92)

Antitoxin

SpoVT-AbrB domain

(8-35)


Sequences

Toxin        


Download         Length: 103 a.a.        Molecular weight: 11323.94 Da        Isoelectric Point: 7.1667

>T285721 WP_082693189.1 NZ_LN865164:c2779908-2779600 [Pseudomonas sp. URMO17WK12:I11]
MCISTVTLMELIYGAEKSSNSERNLTAVEGLAARLEVLTYDRNAAAHTGQLRVELARLGTPIGPFDQMIAGHARSQGLII
VTNNRREFERVPGLRSEDWVIR

Download         Length: 309 bp

Antitoxin


Download         Length: 77 a.a.        Molecular weight: 8658.64 Da        Isoelectric Point: 4.3193

>AT285721 WP_059183628.1 NZ_LN865164:c2780169-2779939 [Pseudomonas sp. URMO17WK12:I11]
MEQGAVFLSNRSQAIRLPKAAAFSEDVKRVDVVAIGRIRIITPAGEAWDSWFDDLAPTEDFMTERDQSADQERERF

Download         Length: 231 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB A0A0S4IAP2

References