285720

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PP_4151-4152/excise(antitoxin)
Location 2215850..2216889 Replicon chromosome
Accession NZ_LN865164
Organism Pseudomonas sp. URMO17WK12:I11 isolate Yellow

Toxin (Protein)


Gene name PP_4152 Uniprot ID -
Locus tag PSHI_RS09925 Protein ID WP_027913401.1
Coordinates 2215850..2216425 (-) Length 192 a.a.

Antitoxin (Protein)


Gene name PP_4151 Uniprot ID A0A0S4I9D6
Locus tag PSHI_RS09930 Protein ID WP_027913402.1
Coordinates 2216422..2216889 (-) Length 156 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PSHI_RS09905 2210931..2212772 + 1842 WP_049695298.1 amidohydrolase -
PSHI_RS09910 2213058..2213969 - 912 WP_027913398.1 LysR family transcriptional regulator -
PSHI_RS09915 2214098..2214895 - 798 WP_059183535.1 SDR family oxidoreductase -
PSHI_RS09920 2214895..2215671 - 777 WP_027913400.1 alpha/beta hydrolase -
PSHI_RS09925 2215850..2216425 - 576 WP_027913401.1 PIN domain-containing protein Toxin
PSHI_RS09930 2216422..2216889 - 468 WP_027913402.1 helix-turn-helix domain-containing protein Antitoxin
PSHI_RS09935 2217102..2218592 - 1491 WP_059183536.1 YifB family Mg chelatase-like AAA ATPase -
PSHI_RS09940 2218825..2220834 + 2010 WP_059184128.1 DUF4034 domain-containing protein -
PSHI_RS09945 2220870..2221127 - 258 WP_027913405.1 accessory factor UbiK family protein -
PSHI_RS09950 2221491..2221829 + 339 WP_002555808.1 P-II family nitrogen regulator -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(8-115)

Antitoxin

SinI-like, DNA-binding domain

(84-130)


Sequences

Toxin        


Download         Length: 192 a.a.        Molecular weight: 21955.26 Da        Isoelectric Point: 5.5909

>T285720 WP_027913401.1 NZ_LN865164:c2216425-2215850 [Pseudomonas sp. URMO17WK12:I11]
MRHSPFTVIYDACVLYPAPLRDLLMHLALTGAYRARWSEQIHDEWTRNVLRNRPDVSETQLYRTVGLMNRAIPDSLVNDY
EPLVQGLDLPDEDDRHVLAAAIKCGASVIVTYNLKDFPAEILKRFEIEALHPDVFLSDIWDLDQAAVLKAVQKQRAALNN
PVYSPRELLDILLKQRLPETVKHLSNYELLI

Download         Length: 576 bp

Antitoxin


Download         Length: 156 a.a.        Molecular weight: 17035.46 Da        Isoelectric Point: 4.9896

>AT285720 WP_027913402.1 NZ_LN865164:c2216889-2216422 [Pseudomonas sp. URMO17WK12:I11]
MTTADLAQAILPDEKAITAAIESSRQIAAFVSTKLDTQRIELVDEAQQRQTVELPTFALRLLGDILNELALGNTVKVVPI
HAELTTQEGADMLNVSRPHLVKLLDEGLIPHTKTGSHRRVKFTDLMAYKADRDKASQAAMDELAAQAQELNMGYQ

Download         Length: 468 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB A0A0S4I9D6

References