Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/-
Location 3455214..3455867 Replicon chromosome
Accession NZ_LN865143
Organism Acinetobacter baumannii isolate CIP70.10

Toxin (Protein)


Gene name cptA Uniprot ID A0A3R9G864
Locus tag ABCIP7010_RS16010 Protein ID WP_000607075.1
Coordinates 3455214..3455603 (-) Length 130 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID V5V966
Locus tag ABCIP7010_RS16015 Protein ID WP_001288210.1
Coordinates 3455610..3455867 (-) Length 86 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
ABCIP7010_RS15995 3450332..3452527 - 2196 WP_001158905.1 TRAP transporter large permease subunit -
ABCIP7010_RS16000 3452715..3453281 - 567 WP_000651536.1 rhombosortase -
ABCIP7010_RS16005 3453359..3454444 - 1086 WP_000049106.1 hypothetical protein -
ABCIP7010_RS16010 3455214..3455603 - 390 WP_000607075.1 membrane protein Toxin
ABCIP7010_RS16015 3455610..3455867 - 258 WP_001288210.1 succinate dehydrogenase assembly factor 2 Antitoxin
ABCIP7010_RS16020 3456055..3457227 + 1173 WP_032028213.1 acyl-CoA dehydrogenase family protein -
ABCIP7010_RS16025 3457276..3458766 - 1491 WP_031966421.1 NAD(P)/FAD-dependent oxidoreductase -
ABCIP7010_RS16030 3458948..3459325 - 378 WP_001216380.1 50S ribosomal protein L17 -
ABCIP7010_RS16035 3459344..3460351 - 1008 WP_000198631.1 DNA-directed RNA polymerase subunit alpha -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Flavinator of succinate dehydrogenase

(10-82)


Sequences

Toxin        


Download         Length: 130 a.a.        Molecular weight: 15649.94 Da        Isoelectric Point: 10.3890

>T285717 WP_000607075.1 NZ_LN865143:c3455603-3455214 [Acinetobacter baumannii]
MINHLNFKLKYSRFSIIFQFFIGLSLAVLFYQLMPLLWWLVVISLLFISFIFFLKRPQLAQIAYLDKKLWSLAYHSQNTI
SRVKILKVIDYQIFIVIYFEGHKTLTSIIWFDQMSLVEWKKLKTLEKLY

Download         Length: 390 bp

Antitoxin


Download         Length: 86 a.a.        Molecular weight: 10318.77 Da        Isoelectric Point: 4.6150

>AT285717 WP_001288210.1 NZ_LN865143:c3455867-3455610 [Acinetobacter baumannii]
MSEEMTLEERKVIYRARRGLKEIDVYFDPYVKNYYLKADPAEKALFAELVEQEDPDLLDWFMEVSEPPRTELRDFIYKLK
HYVHG

Download         Length: 258 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A3R9G864

Antitoxin

Source ID Structure
AlphaFold DB A0A7U4BQM7

References