Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | phd-doc/HTH_IclR(antitoxin) |
| Location | 5764453..5766167 | Replicon | chromosome |
| Accession | NZ_LN854573 | ||
| Organism | Pseudomonas sp. URMO17WK12:I11 isolate Shine | ||
Toxin (Protein)
| Gene name | doc | Uniprot ID | A0A0S4I1W9 |
| Locus tag | AWM52_RS25905 | Protein ID | WP_027923576.1 |
| Coordinates | 5765283..5766167 (-) | Length | 295 a.a. |
Antitoxin (Protein)
| Gene name | phd | Uniprot ID | - |
| Locus tag | AWM52_RS25900 | Protein ID | WP_027923575.1 |
| Coordinates | 5764453..5765286 (-) | Length | 278 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| AWM52_RS25880 | 5759658..5761154 | - | 1497 | WP_027923571.1 | aldehyde dehydrogenase | - |
| AWM52_RS25885 | 5761165..5761968 | - | 804 | WP_027923572.1 | aspartate dehydrogenase | - |
| AWM52_RS25890 | 5761979..5763661 | - | 1683 | WP_059182768.1 | thiamine pyrophosphate-binding protein | - |
| AWM52_RS25895 | 5763654..5764451 | - | 798 | WP_027923574.1 | SDR family oxidoreductase | - |
| AWM52_RS25900 | 5764453..5765286 | - | 834 | WP_027923575.1 | IclR family transcriptional regulator | Antitoxin |
| AWM52_RS25905 | 5765283..5766167 | - | 885 | WP_027923576.1 | alpha/beta hydrolase | Toxin |
| AWM52_RS25910 | 5766172..5766711 | - | 540 | WP_027923577.1 | cupin domain-containing protein | - |
| AWM52_RS25915 | 5766730..5767497 | - | 768 | WP_172825941.1 | SDR family oxidoreductase | - |
| AWM52_RS25920 | 5767494..5768270 | - | 777 | WP_027923579.1 | ABC transporter permease | - |
| AWM52_RS25925 | 5768299..5769300 | - | 1002 | WP_059182769.1 | ABC transporter substrate-binding protein | - |
| AWM52_RS25930 | 5769340..5770191 | - | 852 | WP_027923581.1 | ABC transporter ATP-binding protein | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 295 a.a. Molecular weight: 31410.99 Da Isoelectric Point: 6.7367
>T285716 WP_027923576.1 NZ_LN854573:c5766167-5765283 [Pseudomonas sp. URMO17WK12:I11]
MSYAIDNLVSPLTADLQAQLALNFPVRTLEIAGGRQAFRECGAGPAIVLLHGIGSGSASWLEVAQELGQSARVIAWDAPG
YGDSTPLRSLAPDASDYAERLLQLLDALGIQRCVLVGHSLGAITATAFASGVQQQRISRLVLISPAQGYGHPSRALQRQE
VRNKRLRALEQLSIQQMAEQRSPYMLSPAASPKALAWVRWNMARLNPDGYRQAIELLCSDDLLRHPPLSMPCEVHCGEAD
GITAPESCLTLAKALGATFNLIADAGHASPIEQPYVVAGRLAFAIKESLTGASL
MSYAIDNLVSPLTADLQAQLALNFPVRTLEIAGGRQAFRECGAGPAIVLLHGIGSGSASWLEVAQELGQSARVIAWDAPG
YGDSTPLRSLAPDASDYAERLLQLLDALGIQRCVLVGHSLGAITATAFASGVQQQRISRLVLISPAQGYGHPSRALQRQE
VRNKRLRALEQLSIQQMAEQRSPYMLSPAASPKALAWVRWNMARLNPDGYRQAIELLCSDDLLRHPPLSMPCEVHCGEAD
GITAPESCLTLAKALGATFNLIADAGHASPIEQPYVVAGRLAFAIKESLTGASL
Download Length: 885 bp
Antitoxin
Download Length: 278 a.a. Molecular weight: 30858.43 Da Isoelectric Point: 6.6450
>AT285716 WP_027923575.1 NZ_LN854573:c5765286-5764453 [Pseudomonas sp. URMO17WK12:I11]
MNDSDLLKDAQDKYIVPGLERGLLLLCEFSRRNRTLTAPELARRLALPRSTIFRLLSTLETMGFVTRSGNEYRLGMSVLR
LGFEYLASLELTELGQPLLARLCDRLNYPSNLVVRDGRSIVYVAKVSPPSVFSSAVNVGTRLPAHATVLGRILLEDLSLA
ELRELYPEDHLEQFSPCTPKTVMELFDLVQADRQRGFVSSEGFFESTISTVAAPVRDETSRIVAALGVTIPTAQIAHVNF
NELLLQVRRSADELSRLLNYNSAAAHDGHRVTALMRD
MNDSDLLKDAQDKYIVPGLERGLLLLCEFSRRNRTLTAPELARRLALPRSTIFRLLSTLETMGFVTRSGNEYRLGMSVLR
LGFEYLASLELTELGQPLLARLCDRLNYPSNLVVRDGRSIVYVAKVSPPSVFSSAVNVGTRLPAHATVLGRILLEDLSLA
ELRELYPEDHLEQFSPCTPKTVMELFDLVQADRQRGFVSSEGFFESTISTVAAPVRDETSRIVAALGVTIPTAQIAHVNF
NELLLQVRRSADELSRLLNYNSAAAHDGHRVTALMRD
Download Length: 834 bp
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|