Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) tsbAT/-
Location 1907223..1907996 Replicon chromosome
Accession NZ_LN854556
Organism Staphylococcus aureus strain B155

Toxin (Protein)


Gene name tsbT Uniprot ID -
Locus tag SABB155_RS09360 Protein ID WP_054189550.1
Coordinates 1907223..1907372 (-) Length 50 a.a.

Antitoxin (Protein)


Gene name tsbA Uniprot ID A0A0D1IYN8
Locus tag SABB155_RS09365 Protein ID WP_001251219.1
Coordinates 1907397..1907996 (-) Length 200 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
SABB155_RS09345 1903294..1904115 + 822 WP_054189552.1 RluA family pseudouridine synthase -
SABB155_RS09350 1904582..1905967 - 1386 WP_054189551.1 class II fumarate hydratase -
SABB155_RS09355 1906163..1906558 - 396 WP_000901023.1 hypothetical protein -
SABB155_RS09360 1907223..1907372 - 150 WP_054189550.1 hypothetical protein Toxin
SABB155_RS09365 1907397..1907996 - 600 WP_001251219.1 glucosamine-6-phosphate isomerase Antitoxin
SABB155_RS09370 1908155..1908625 - 471 WP_000181394.1 tRNA (uridine(34)/cytosine(34)/5- carboxymethylaminomethyluridine(34)-2'-O)- methyltransferase TrmL -
SABB155_RS09375 1908630..1909757 - 1128 WP_054189549.1 tRNA epoxyqueuosine(34) reductase QueG -
SABB155_RS09380 1909908..1910630 - 723 WP_054189583.1 amino acid ABC transporter ATP-binding protein -
SABB155_RS09385 1910623..1912080 - 1458 WP_054189548.1 ABC transporter permease subunit -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Glucosamine-6-phosphate isomerase

(124-196)


Sequences

Toxin        


Download         Length: 50 a.a.        Molecular weight: 5862.20 Da        Isoelectric Point: 3.9075

>T285701 WP_054189550.1 NZ_LN854556:c1907372-1907223 [Staphylococcus aureus]
MSKDKDPKLNYHEEENSMVNDFEDLKELGKEMEQISDQNEQEKNSEEDN

Download         Length: 150 bp

Antitoxin


Download         Length: 200 a.a.        Molecular weight: 22357.50 Da        Isoelectric Point: 5.1445

>AT285701 WP_001251219.1 NZ_LN854556:c1907996-1907397 [Staphylococcus aureus]
MAMNFKVFDNSQLVAEYAADIIRKQFNNNPTTIAGFHLDTDQAPVLDELKKNIEKHAVDFSQINILDYDDKKSYFEALGV
PAGQVYPIAYEKDAIELIADKIKTKENKGKLTLQVVSIDEQGKLNVSIRQGLMEAREIFLVVTGANKRDVVEKLYQENGK
TSFEPADLKAHRMVNVILDKEAAAGLPEDVKAYFTSRFA

Download         Length: 600 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB A0A0D1IYN8

References