285695

Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type II Classification (family/domain) TsaAT/-
Location 822951..823428 Replicon chromosome
Accession NZ_LN854556
Organism Staphylococcus aureus strain B155

Toxin (Protein)


Gene name TsaT Uniprot ID T1Y7S2
Locus tag SABB155_RS04000 Protein ID WP_000052076.1
Coordinates 822951..823139 (-) Length 63 a.a.

Antitoxin (Protein)


Gene name TsaA Uniprot ID -
Locus tag SABB155_RS04005 Protein ID WP_001059689.1
Coordinates 823168..823428 (-) Length 87 a.a.

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
SABB155_RS03970 818901..819458 + 558 WP_054189291.1 hypothetical protein -
SABB155_RS03975 819800..820486 + 687 WP_054189292.1 thermonuclease family protein -
SABB155_RS03980 820843..821043 + 201 WP_061745596.1 cold-shock protein -
SABB155_RS03985 821541..821759 - 219 WP_054189293.1 hypothetical protein -
SABB155_RS03990 821821..822105 - 285 WP_054189294.1 hypothetical protein -
SABB155_RS03995 822193..822762 - 570 WP_054189295.1 hypothetical protein -
SABB155_RS04000 822951..823139 - 189 WP_000052076.1 hypothetical protein Toxin
SABB155_RS04005 823168..823428 - 261 WP_001059689.1 hypothetical protein Antitoxin
SABB155_RS04010 823769..823972 + 204 WP_000145163.1 sterile alpha motif-like domain-containing protein -
SABB155_RS04015 823969..824205 - 237 WP_000368687.1 hypothetical protein -
SABB155_RS04020 824429..825010 + 582 WP_054189296.1 phosphoglycerate mutase family protein -
SABB155_RS04025 825083..825700 - 618 WP_054189297.1 LysE/ArgO family amino acid transporter -
SABB155_RS04030 825856..826350 - 495 WP_054189298.1 GNAT family N-acetyltransferase -
SABB155_RS04035 826749..827171 - 423 WP_000974455.1 organic hydroperoxide resistance protein -
SABB155_RS04040 827319..828035 + 717 WP_054189299.1 type I 3-dehydroquinate dehydratase -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin


No domain identified.


Antitoxin


No domain identified.



Sequences


Toxin        


Download         Length: 63 a.a.        Molecular weight: 7142.82 Da        Isoelectric Point: 9.9971

>T285695 WP_000052076.1 NZ_LN854556:c823139-822951 [Staphylococcus aureus]
MSLHFAILFWLALIFLVAATFILVLMKKTGKESKKESYLSFTVILYIFGFAILIYTFIFGVL

Download         Length: 189 bp


Antitoxin


Download         Length: 87 a.a.        Molecular weight: 10009.20 Da        Isoelectric Point: 4.4986

>AT285695 WP_001059689.1 NZ_LN854556:c823428-823168 [Staphylococcus aureus]
MNNILLNAINIVITTTFVIFNILITYNKDLDDLCWLLPGIIICGVILIVSFTIAMITKNWLSEILFFINIVLVLYYIYPI
FYRFIG

Download         Length: 261 bp


Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure
AlphaFold DB A0A0E0VP18


Antitoxin

Source ID Structure

References