Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-YafN
Location 3599533..3600052 Replicon chromosome
Accession NZ_LN847264
Organism Pseudomonas sp. CCOS 191

Toxin (Protein)


Gene name relE Uniprot ID A0A0F7Y3G5
Locus tag CCOS191_RS15865 Protein ID WP_046856044.1
Coordinates 3599533..3599817 (-) Length 95 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID A0A0F7XZJ5
Locus tag CCOS191_RS15870 Protein ID WP_046857823.1
Coordinates 3599807..3600052 (-) Length 82 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CCOS191_RS15845 3594824..3595861 - 1038 WP_046856040.1 histone deacetylase family protein -
CCOS191_RS15850 3595861..3597102 - 1242 WP_046856041.1 Zn-dependent hydrolase -
CCOS191_RS15855 3597119..3598423 - 1305 WP_046856042.1 MHS family MFS transporter -
CCOS191_RS15860 3598607..3599524 + 918 WP_046856043.1 LysR family transcriptional regulator -
CCOS191_RS15865 3599533..3599817 - 285 WP_046856044.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
CCOS191_RS15870 3599807..3600052 - 246 WP_046857823.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
CCOS191_RS15875 3600132..3600872 - 741 WP_046856045.1 hypothetical protein -
CCOS191_RS15880 3601237..3604632 + 3396 WP_046856046.1 multicopper oxidase domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Genomic island - - 3586039..3627953 41914


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(5-83)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(9-77)


Sequences

Toxin        


Download         Length: 95 a.a.        Molecular weight: 10936.83 Da        Isoelectric Point: 10.9886

>T285683 WP_046856044.1 NZ_LN847264:c3599817-3599533 [Pseudomonas sp. CCOS 191]
MTYKLEFLPSALKEWKKLGHTVREQARRKLKERLLSPRVGADAMRDLPDHFKIKLKASGYRVVYRVEDDRVVVVVVAIGK
RERGQAYRSAADRL

Download         Length: 285 bp

Antitoxin


Download         Length: 82 a.a.        Molecular weight: 8875.34 Da        Isoelectric Point: 4.4000

>AT285683 WP_046857823.1 NZ_LN847264:c3600052-3599807 [Pseudomonas sp. CCOS 191]
MQNIFADVTVSVSELKKNPTAVMADAQGKPVAVLNHNRVMGYMVPAELYEAMMERLEDMELAALVKARAGEKGIPVELDD
L

Download         Length: 246 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A0F7Y3G5

Antitoxin

Source ID Structure
AlphaFold DB A0A0F7XZJ5

References