285681

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PumA-relB/upstrm_HI1419-dnstrm_HI1420
Location 326357..326962 Replicon chromosome
Accession NZ_LN847264
Organism Pseudomonas sp. CCOS 191

Toxin (Protein)


Gene name PumA Uniprot ID A0A0F7Y1Z8
Locus tag CCOS191_RS01580 Protein ID WP_046853797.1
Coordinates 326357..326647 (+) Length 97 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag CCOS191_RS01585 Protein ID WP_046853798.1
Coordinates 326657..326962 (+) Length 102 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CCOS191_RS01560 321797..322570 - 774 WP_046853793.1 ABC transporter ATP-binding protein -
CCOS191_RS01565 323177..324562 + 1386 WP_046853794.1 GABA permease -
CCOS191_RS01570 324649..325092 - 444 WP_046853795.1 hypothetical protein -
CCOS191_RS01575 325182..326063 - 882 WP_172670913.1 polyphosphate kinase 2 -
CCOS191_RS01580 326357..326647 + 291 WP_046853797.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
CCOS191_RS01585 326657..326962 + 306 WP_046853798.1 putative addiction module antidote protein Antitoxin
CCOS191_RS01595 327242..327514 - 273 WP_011536185.1 oxidative damage protection protein -
CCOS191_RS01600 327511..328578 - 1068 WP_046853799.1 A/G-specific adenine glycosylase -
CCOS191_RS01605 328575..330824 - 2250 WP_046853800.1 AsmA family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 307248..333744 26496


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Addiction module killer protein, predicted

(1-95)

Antitoxin

Cro/C1-type helix-turn-helix domain

(46-90)


Sequences

Toxin        


Download         Length: 97 a.a.        Molecular weight: 10898.73 Da        Isoelectric Point: 10.5526

>T285681 WP_046853797.1 NZ_LN847264:326357-326647 [Pseudomonas sp. CCOS 191]
MHTLIQTDRYKKWFAALRDARAQARINVRLRRVELGVLGDCKPVGEGVLELRVDYGPGYRVYLARRGYEVILLLAGGDKT
TQARDIKSALKLARDI

Download         Length: 291 bp

Antitoxin


Download         Length: 102 a.a.        Molecular weight: 10653.35 Da        Isoelectric Point: 5.0621

>AT285681 WP_046853798.1 NZ_LN847264:326657-326962 [Pseudomonas sp. CCOS 191]
MADLKLTKWDAADHLKTEQDVVLYLEACLEENDPVLLAAALGDIARARGMAQLARDTGLTREGLYKALSAEGNPSLATIM
KVMAALGVRLHAGAVPPQVAG

Download         Length: 306 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A0F7Y1Z8

Antitoxin

Source ID Structure

References