Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) mazEF/MazF(toxin)
Location 1568389..1568994 Replicon chromosome
Accession NZ_LN831776
Organism Paenibacillus riograndensis SBR5 isolate SBR5(T)

Toxin (Protein)


Gene name mazF Uniprot ID A0A0E4H7G2
Locus tag PRIO_RS06820 Protein ID WP_019913013.1
Coordinates 1568644..1568994 (+) Length 117 a.a.

Antitoxin (Protein)


Gene name mazE Uniprot ID -
Locus tag PRIO_RS06815 Protein ID WP_174469047.1
Coordinates 1568389..1568640 (+) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PRIO_RS06805 1565655..1566740 + 1086 WP_020427628.1 outer membrane lipoprotein carrier protein LolA -
PRIO_RS06810 1566964..1568145 + 1182 WP_020427627.1 alanine racemase -
PRIO_RS06815 1568389..1568640 + 252 WP_174469047.1 ribbon-helix-helix protein, CopG family Antitoxin
PRIO_RS06820 1568644..1568994 + 351 WP_019913013.1 type II toxin-antitoxin system PemK/MazF family toxin Toxin
PRIO_RS06825 1569407..1570711 + 1305 WP_039787242.1 extracellular solute-binding protein -
PRIO_RS06830 1570819..1571703 + 885 WP_020427624.1 sugar ABC transporter permease -
PRIO_RS06835 1571706..1572533 + 828 WP_020427623.1 carbohydrate ABC transporter permease -
PRIO_RS06840 1572567..1573385 + 819 WP_020427622.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase PemK-like

(4-111)

Antitoxin

Ribbon-helix-helix protein, CopG

(2-35)


Sequences

Toxin        


Download         Length: 117 a.a.        Molecular weight: 12749.67 Da        Isoelectric Point: 4.8265

>T285646 WP_019913013.1 NZ_LN831776:1568644-1568994 [Paenibacillus riograndensis SBR5]
MIVKRGDVFFADLSPVVGSEQGGVRPVLVIQNDIGNRFSPTVIVAAITAQIQKAKLPTHVEIDAAAHGFDRDSVILLEQV
RTIDKQRLTDKITHLDDETMKLVDDSLQISLGLIDF

Download         Length: 351 bp

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9487.94 Da        Isoelectric Point: 5.1051

>AT285646 WP_174469047.1 NZ_LN831776:1568389-1568640 [Paenibacillus riograndensis SBR5]
MISLPDHLLQEVDGIVQLENSNRSELIRQAMKLYLSERRKRTIRDSMQRGYMEMAKINLTMACEAFLAEEDADSTLGRLV
SGV

Download         Length: 252 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A0E4H7G2

Antitoxin

Source ID Structure

References