Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) mazEF/PRK09907-MazE
Location 970428..970993 Replicon chromosome
Accession NZ_LN831776
Organism Paenibacillus riograndensis SBR5 isolate SBR5(T)

Toxin (Protein)


Gene name mazF Uniprot ID A0A0E4CUN9
Locus tag PRIO_RS04215 Protein ID WP_020426982.1
Coordinates 970652..970993 (+) Length 114 a.a.

Antitoxin (Protein)


Gene name mazE Uniprot ID -
Locus tag PRIO_RS04210 Protein ID WP_020426981.1
Coordinates 970428..970658 (+) Length 77 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PRIO_RS04205 969242..970231 + 990 WP_046501200.1 tRNA-dihydrouridine synthase -
PRIO_RS04210 970428..970658 + 231 WP_020426981.1 AbrB/MazE/SpoVT family DNA-binding domain-containing protein Antitoxin
PRIO_RS04215 970652..970993 + 342 WP_020426982.1 endoribonuclease MazF Toxin
PRIO_RS04220 971322..971888 + 567 WP_020426983.1 hypothetical protein -
PRIO_RS04225 972026..973036 + 1011 WP_020426984.1 sugar-binding protein -
PRIO_RS04230 973243..975090 + 1848 WP_020426985.1 sensor histidine kinase -
PRIO_RS04235 975087..975941 + 855 WP_020426986.1 response regulator -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Genomic island - - 925550..1009221 83671


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase PemK-like

(6-112)

Antitoxin

Antitoxin PemI-like

(2-76)


Sequences

Toxin        


Download         Length: 114 a.a.        Molecular weight: 12482.58 Da        Isoelectric Point: 7.8216

>T285645 WP_020426982.1 NZ_LN831776:970652-970993 [Paenibacillus riograndensis SBR5]
MVTGGYVPDRGDLIWLQFNPQAGHEQAGKRPALVVSPASYNRKVGLSLLCPVTSKQKDYPFEVVIPQDLPIEGVILADQV
KSLDWQSRQAAFICKVPQIILSDVVAKLDLLIR

Download         Length: 342 bp

Antitoxin


Download         Length: 77 a.a.        Molecular weight: 8447.52 Da        Isoelectric Point: 4.5637

>AT285645 WP_020426981.1 NZ_LN831776:970428-970658 [Paenibacillus riograndensis SBR5]
MFQVQKWGNSLGIRIPKSLALKVGIEEGSEVDLDVEDGHLIIKPKSATLDEILSQVTPDNLHHEVSTGEQQGREVW

Download         Length: 231 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A0E4CUN9

Antitoxin

Source ID Structure

References