285620

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) TsaAT/-
Location 849121..849598 Replicon chromosome
Accession NZ_LN831036
Organism Staphylococcus aureus strain NCTC13435

Toxin (Protein)


Gene name TsaT Uniprot ID T1Y7S2
Locus tag AT694_RS04095 Protein ID WP_000052076.1
Coordinates 849121..849309 (-) Length 63 a.a.

Antitoxin (Protein)


Gene name TsaA Uniprot ID T1Y6P8
Locus tag AT694_RS04100 Protein ID WP_001059690.1
Coordinates 849338..849598 (-) Length 87 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
AT694_RS04065 845163..845633 + 471 WP_000824472.1 hypothetical protein -
AT694_RS04070 845974..846660 + 687 WP_001566557.1 thermonuclease family protein -
AT694_RS04075 847017..847217 + 201 WP_001059082.1 cold-shock protein -
AT694_RS04080 847712..847930 - 219 WP_000005884.1 hypothetical protein -
AT694_RS04085 847992..848276 - 285 WP_001004394.1 hypothetical protein -
AT694_RS04090 848364..848933 - 570 WP_001106652.1 hypothetical protein -
AT694_RS04095 849121..849309 - 189 WP_000052076.1 hypothetical protein Toxin
AT694_RS04100 849338..849598 - 261 WP_001059690.1 hypothetical protein Antitoxin
AT694_RS04105 849939..850142 + 204 WP_000145163.1 sterile alpha motif-like domain-containing protein -
AT694_RS04110 850139..850375 - 237 WP_000368687.1 hypothetical protein -
AT694_RS04115 850600..851181 + 582 WP_001140697.1 phosphoglycerate mutase family protein -
AT694_RS04120 851254..851871 - 618 WP_000255553.1 LysE/ArgO family amino acid transporter -
AT694_RS04125 852027..852521 - 495 WP_000569884.1 GNAT family N-acetyltransferase -
AT694_RS04130 852920..853342 - 423 WP_000974465.1 organic hydroperoxide resistance protein -
AT694_RS04135 853490..854206 + 717 WP_000150020.1 type I 3-dehydroquinate dehydratase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 63 a.a.        Molecular weight: 7142.82 Da        Isoelectric Point: 9.9971

>T285620 WP_000052076.1 NZ_LN831036:c849309-849121 [Staphylococcus aureus]
MSLHFAILFWLALIFLVAATFILVLMKKTGKESKKESYLSFTVILYIFGFAILIYTFIFGVL

Download         Length: 189 bp

Antitoxin


Download         Length: 87 a.a.        Molecular weight: 9940.09 Da        Isoelectric Point: 4.0624

>AT285620 WP_001059690.1 NZ_LN831036:c849598-849338 [Staphylococcus aureus]
MNNILLNAINIVITTTFVIFNILITYNKDLDDLCWLLPGIIICGVILIVSFTIAMITKNWLSEILFFINIVLVLYYIYPI
FYSFIG

Download         Length: 261 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A0E0VP18

Antitoxin

Source ID Structure
AlphaFold DB A0A0E0VN56

References