Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RelE-RelB
Location 5468333..5468897 Replicon chromosome
Accession NZ_LN831029
Organism Achromobacter xylosoxidans strain NCTC10807

Toxin (Protein)


Gene name relE Uniprot ID A0A0D6IHV7
Locus tag AT699_RS24630 Protein ID WP_020926667.1
Coordinates 5468333..5468614 (-) Length 94 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID A0A0D6IHW1
Locus tag AT699_RS24635 Protein ID WP_020926666.1
Coordinates 5468601..5468897 (-) Length 99 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
AT699_RS24605 5463365..5463868 - 504 WP_006386642.1 flavin reductase family protein -
AT699_RS24610 5463891..5464904 - 1014 WP_024070172.1 LLM class flavin-dependent oxidoreductase -
AT699_RS24615 5465026..5465859 + 834 WP_024070173.1 IclR family transcriptional regulator -
AT699_RS24620 5466095..5467150 + 1056 WP_054442897.1 tRNA preQ1(34) S-adenosylmethionine ribosyltransferase-isomerase QueA -
AT699_RS24625 5467147..5468283 + 1137 WP_024070175.1 tRNA guanosine(34) transglycosylase Tgt -
AT699_RS24630 5468333..5468614 - 282 WP_020926667.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
AT699_RS24635 5468601..5468897 - 297 WP_020926666.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
AT699_RS24640 5469269..5469613 + 345 WP_006386647.1 preprotein translocase subunit YajC -
AT699_RS24645 5469729..5471609 + 1881 WP_006386648.1 protein translocase subunit SecD -
AT699_RS24650 5471661..5472596 + 936 WP_006386649.1 protein translocase subunit SecF -
AT699_RS31230 5472766..5473134 + 369 WP_006386650.1 type II toxin-antitoxin system RelE/ParE family toxin -
AT699_RS24660 5473131..5473442 + 312 WP_006386651.1 helix-turn-helix domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-90)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(4-52)


Sequences

Toxin        


Download         Length: 94 a.a.        Molecular weight: 10262.77 Da        Isoelectric Point: 7.0080

>T285610 WP_020926667.1 NZ_LN831029:c5468614-5468333 [Achromobacter xylosoxidans]
VPAVEWSSAARADLLAIVDYISDDNPDAAQRLKDDIETKAAQLPARPALYRPGRIAGTREMVVRANYIIVYAADALAVRI
LRILHAAQQWPPQ

Download         Length: 282 bp

Antitoxin


Download         Length: 99 a.a.        Molecular weight: 10717.24 Da        Isoelectric Point: 7.3208

>AT285610 WP_020926666.1 NZ_LN831029:c5468897-5468601 [Achromobacter xylosoxidans]
MPQTSMLHVRVDDKLKADATEKLAEFGLTISDAVRILLTRVAKEGGLPAGLTTDAQAHDAWFRAKVQEALADTGPAVPHQ
QVMDEAQALIDRKRRARS

Download         Length: 297 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A0D6IHV7

Antitoxin

Source ID Structure
AlphaFold DB A0A0D6IHW1

References