Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-VapB
Location 1077093..1077666 Replicon chromosome
Accession NZ_LN831029
Organism Achromobacter xylosoxidans strain NCTC10807

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag AT699_RS04915 Protein ID WP_058207222.1
Coordinates 1077289..1077666 (+) Length 126 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag AT699_RS30790 Protein ID WP_054471260.1
Coordinates 1077093..1077302 (+) Length 70 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
AT699_RS04895 1072499..1073287 - 789 WP_024067852.1 helix-turn-helix transcriptional regulator -
AT699_RS04900 1073386..1074312 + 927 WP_020924995.1 DMT family transporter -
AT699_RS04905 1074325..1075143 - 819 WP_058207221.1 AAC(3) family N-acetyltransferase -
AT699_RS04910 1075295..1076968 + 1674 WP_024067854.1 energy-dependent translational throttle protein EttA -
AT699_RS30790 1077093..1077302 + 210 WP_054471260.1 type II toxin-antitoxin system VapB family antitoxin Antitoxin
AT699_RS04915 1077289..1077666 + 378 WP_058207222.1 type II toxin-antitoxin system VapC family toxin Toxin
AT699_RS04920 1077734..1078267 + 534 WP_024067855.1 isochorismatase family protein -
AT699_RS04925 1078458..1078682 + 225 WP_006388976.1 glycine zipper 2TM domain-containing protein -
AT699_RS04930 1078812..1079069 - 258 WP_006388977.1 cell division topological specificity factor MinE -
AT699_RS04935 1079073..1079888 - 816 WP_006388978.1 septum site-determining protein MinD -
AT699_RS04940 1080077..1080994 - 918 WP_024067857.1 septum site-determining protein MinC -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Bacterial antitoxin of type II TA system, VapB

(2-44)


Sequences

Toxin        


Download         Length: 126 a.a.        Molecular weight: 13890.17 Da        Isoelectric Point: 6.3726

>T285607 WP_058207222.1 NZ_LN831029:1077289-1077666 [Achromobacter xylosoxidans]
MILVDTSIWIDHLSDGEPCLVRLLEEESVLMHPFIAGELALGSLGRRDVVLGTMSLLPQVVRASHDEVMHFLHSERLFGK
GIGYVDLHLLASTRLTPGAALWTREKRLQALATTLSLAVDPPRYH

Download         Length: 378 bp

Antitoxin


Download         Length: 70 a.a.        Molecular weight: 7521.62 Da        Isoelectric Point: 9.9435

>AT285607 WP_054471260.1 NZ_LN831029:1077093-1077302 [Achromobacter xylosoxidans]
VRTTVTLDDDLLELARTYTGVQETSALVTRALTQLVQKEAAKRLAKLGGSSPKLKPIPRRQTETCNDPG

Download         Length: 210 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References