Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) mazEF/PRK09907-MazE
Location 2941944..2942524 Replicon chromosome
Accession NC_019753
Organism Crinalium epipsammum PCC 9333

Toxin (Protein)


Gene name mazF Uniprot ID -
Locus tag CRI9333_RS12815 Protein ID WP_198013665.1
Coordinates 2942189..2942524 (+) Length 112 a.a.

Antitoxin (Protein)


Gene name mazE Uniprot ID -
Locus tag CRI9333_RS12810 Protein ID WP_041226637.1
Coordinates 2941944..2942186 (+) Length 81 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CRI9333_RS12785 2937295..2937570 - 276 WP_198013568.1 class II glutamine amidotransferase -
CRI9333_RS12790 2938306..2938707 + 402 WP_015203588.1 hypothetical protein -
CRI9333_RS12795 2938827..2939291 - 465 WP_015203589.1 DNA-binding protein -
CRI9333_RS12800 2939801..2941072 - 1272 WP_015203590.1 tyrosine-type recombinase/integrase -
CRI9333_RS12805 2941136..2941714 - 579 WP_083890030.1 class II glutamine amidotransferase -
CRI9333_RS12810 2941944..2942186 + 243 WP_041226637.1 AbrB/MazE/SpoVT family DNA-binding domain-containing protein Antitoxin
CRI9333_RS12815 2942189..2942524 + 336 WP_198013665.1 type II toxin-antitoxin system PemK/MazF family toxin Toxin
CRI9333_RS12820 2942592..2942960 - 369 WP_015203593.1 DUF5615 family PIN-like protein -
CRI9333_RS12825 2942944..2943186 - 243 WP_015203594.1 DUF433 domain-containing protein -
CRI9333_RS12830 2943245..2944951 - 1707 WP_015203595.1 AIPR family protein -
CRI9333_RS12835 2945089..2947017 - 1929 WP_015203596.1 cyclomaltodextrin glucanotransferase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase PemK-like

(7-107)

Antitoxin

Antitoxin PemI-like

(4-80)


Sequences

Toxin        


Download         Length: 112 a.a.        Molecular weight: 12324.29 Da        Isoelectric Point: 6.3106

>T28560 WP_198013665.1 NC_019753:2942189-2942524 [Crinalium epipsammum PCC 9333]
IAGRVPERGDIIQVQLNPRTGSEQAGYRPAVVISPAAYNQISKLVLICPITNRQKGWPFEVELPTSMKTSGVVLVDQIRT
IDCDARKADFVEKAPLEWVDEVLARLEPLVK

Download         Length: 336 bp

>T28560 NC_019753:2942189-2942524 [Crinalium epipsammum PCC 9333]
ATTGCAGGGCGTGTTCCTGAACGTGGAGATATCATTCAGGTACAACTAAATCCGAGAACAGGTAGCGAGCAAGCAGGTTA
TCGTCCTGCTGTTGTCATCTCTCCTGCGGCTTATAACCAAATCTCTAAATTAGTTTTGATTTGTCCGATTACGAACCGTC
AAAAAGGATGGCCATTTGAAGTTGAATTACCAACGTCAATGAAAACCTCTGGAGTCGTTTTAGTTGATCAGATTAGAACA
ATTGACTGTGATGCCAGAAAAGCTGATTTTGTAGAAAAAGCTCCTCTAGAATGGGTTGATGAAGTTTTAGCCAGACTAGA
ACCTTTAGTCAAATAA

Antitoxin


Download         Length: 81 a.a.        Molecular weight: 9322.59 Da        Isoelectric Point: 4.1509

>AT28560 WP_041226637.1 NC_019753:2941944-2942186 [Crinalium epipsammum PCC 9333]
MLTQKVSWWGNSLGLRLPQTLVQQVEWTEGTIVSITIEDNRLVLSPVKPKYRLEQLLENITPDMQHDEMEWGEAVGEETW

Download         Length: 243 bp

>AT28560 NC_019753:2941944-2942186 [Crinalium epipsammum PCC 9333]
ATGCTCACCCAAAAAGTCAGTTGGTGGGGAAACTCCCTCGGACTTCGACTACCGCAAACGCTTGTGCAACAGGTTGAATG
GACTGAAGGAACAATAGTTTCAATTACAATTGAAGACAATCGGTTGGTTCTGTCTCCCGTAAAACCCAAGTACCGCTTAG
AGCAGTTGCTTGAAAACATCACTCCTGATATGCAACATGATGAGATGGAGTGGGGAGAAGCTGTGGGAGAAGAAACTTGG
TAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References