Detailed information of TA system TA028558

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relBE/-
• Location: 1059565..1060174
• Replicon: chromosome
• Accession: NC_019753
• Organism: Crinalium epipsammum PCC 9333

Toxin (Protein)

• Gene name: relE
• Uniprot ID: K9VWC1
• Locus tag: CRI9333_RS04530
• Protein ID: WP_015201981.1
• Coordinates: 1059809..1060174 (+)
• Length: 122 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: K9VUR9
• Locus tag: CRI9333_RS04525
• Protein ID: WP_015201980.1
• Coordinates: 1059565..1059819 (+)
• Length: 85 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
CRI9333_RS04505	1055239..1055970	+	732	WP_015201976.1	photosystem II biogenesis protein Psp29	-
CRI9333_RS04510	1056098..1056415	-	318	WP_015201977.1	thioredoxin	-
CRI9333_RS04515	1056565..1057329	+	765	WP_015201978.1	3-oxoacyl-[acyl-carrier-protein] reductase	-
CRI9333_RS04520	1057585..1059261	+	1677	WP_015201979.1	chaperonin GroEL	-
CRI9333_RS04525	1059565..1059819	+	255	WP_015201980.1	hypothetical protein	Antitoxin
CRI9333_RS04530	1059809..1060174	+	366	WP_015201981.1	hypothetical protein	Toxin
CRI9333_RS04535	1060321..1061493	+	1173	WP_015201982.1	magnesium/cobalt transporter CorA	-
CRI9333_RS24715	1061543..1062220	+	678	WP_015201983.1	hypothetical protein	-
CRI9333_RS04545	1062692..1063006	-	315	WP_015201984.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• mRNA interferase PemK-like (4-111)

Antitoxin

• Ribbon-helix-helix protein, CopG (12-45)

Sequences

Toxin

Protein

• Length: 122 a.a.
• Molecular weight: 14058.97 Da
• Isoelectric Point: 8.3350

>T28558 WP_015201981.1 NC_019753:1059809-1060174 [Crinalium epipsammum PCC 9333]
MLNNNNQISIRFADEFENNLYTLSKKYRRIRADVEPVIEQIQTGNFIGDRIANLGENYFVLKVRVKNSNLHKGKRAGYRL
IYQLESPTSILLLTIYSKLDREDISTNEIYGIIAEFNGNEL

Nucleotide

• Length: 366 bp

>T28558 NC_019753:1059809-1060174 [Crinalium epipsammum PCC 9333]
ATGCTGAATAACAATAATCAAATCTCTATCCGTTTCGCTGATGAATTTGAAAACAACCTATATACTTTATCTAAAAAGTA
TCGTCGTATTCGTGCAGACGTTGAACCAGTAATTGAGCAAATTCAGACAGGGAACTTTATTGGAGACCGTATTGCTAATC
TAGGTGAAAATTATTTTGTACTTAAGGTAAGAGTTAAAAACAGTAACCTTCACAAAGGAAAACGTGCAGGTTATCGGCTA
ATTTATCAACTTGAATCGCCTACTAGCATACTTTTATTAACTATTTATTCTAAGTTAGATAGAGAAGATATTAGTACTAA
CGAAATTTATGGCATTATAGCTGAATTTAATGGAAATGAATTATGA

Antitoxin

Protein

• Length: 85 a.a.
• Molecular weight: 9475.60 Da
• Isoelectric Point: 4.0434

>AT28558 WP_015201980.1 NC_019753:1059565-1059819 [Crinalium epipsammum PCC 9333]
MKAVEVTGNIDEKGQLFLDEPIEVETPSKVRVIVLFTEPNDQLESDPDDTPIEEIKASLRRALQEAKAGQTRPLSELWDR
IDAE

Nucleotide

• Length: 255 bp

>AT28558 NC_019753:1059565-1059819 [Crinalium epipsammum PCC 9333]
ATGAAAGCAGTTGAAGTCACCGGAAATATTGATGAAAAAGGGCAACTATTTTTAGACGAACCTATAGAGGTAGAAACCCC
TAGTAAAGTGCGAGTTATAGTTCTATTTACTGAACCTAATGATCAATTAGAATCTGACCCCGATGATACTCCTATTGAAG
AGATAAAAGCTAGTCTGAGAAGAGCTTTACAAGAAGCTAAAGCTGGACAAACTCGACCACTATCTGAACTGTGGGATAGA
ATTGATGCTGAATAA

Structures

Toxin

• AlphaFold DB: K9VWC1

Antitoxin

• AlphaFold DB: K9VUR9