Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 3364755..3364900 Replicon chromosome
Accession NZ_LN824133
Organism Klebsiella pneumoniae strain MS6671

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 3364762..3364864 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 3364755..3364900 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
MS6671_RS16730 3360286..3361719 + 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
MS6671_RS16735 3361835..3362074 + 240 WP_002911393.1 YebV family protein -
MS6671_RS16740 3362172..3362363 + 192 WP_002911395.1 YebW family protein -
MS6671_RS16745 3362360..3363013 - 654 WP_024622748.1 protein-serine/threonine phosphatase -
MS6671_RS16750 3363170..3364138 + 969 WP_014907334.1 VirK/YbjX family protein -
MS6671_RS32505 3364243..3364386 + 144 WP_038431282.1 Ecr family regulatory small membrane protein -
- 3364755..3364900 + 146 - - Antitoxin
- 3364762..3364864 - 103 - - Toxin
MS6671_RS16760 3365023..3365361 - 339 WP_002911404.1 YebY family protein -
MS6671_RS16765 3365378..3366247 - 870 WP_004175431.1 copper homeostasis membrane protein CopD -
MS6671_RS16770 3366251..3366625 - 375 WP_039819395.1 CopC domain-containing protein YobA -
MS6671_RS16775 3366738..3366968 + 231 WP_002911406.1 DNA polymerase III subunit theta -
MS6671_RS16780 3367047..3367706 + 660 WP_002911407.1 exodeoxyribonuclease X -
MS6671_RS16785 3367710..3369770 - 2061 WP_004151449.1 oligopeptidase B -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T285578 NZ_LN824133:c3364864-3364762 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT285578 NZ_LN824133:3364755-3364900 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References