Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) parDE/ParE-RHH
Location 2126089..2126630 Replicon chromosome
Accession NZ_LN813019
Organism Halomonas sp. R57-5

Toxin (Protein)


Gene name parE Uniprot ID A0A0D6E807
Locus tag HALO_RS09720 Protein ID WP_035580252.1
Coordinates 2126089..2126388 (-) Length 100 a.a.

Antitoxin (Protein)


Gene name parD Uniprot ID A0A0D6E7C4
Locus tag HALO_RS09725 Protein ID WP_035580249.1
Coordinates 2126388..2126630 (-) Length 81 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HALO_RS09695 2121894..2122229 + 336 WP_022522982.1 YqcC family protein -
HALO_RS09700 2122310..2122936 - 627 WP_035580258.1 outer membrane beta-barrel protein -
HALO_RS09705 2123494..2124192 + 699 WP_081899087.1 HNH endonuclease -
HALO_RS09715 2125571..2126038 + 468 WP_050713372.1 hypothetical protein -
HALO_RS09720 2126089..2126388 - 300 WP_035580252.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
HALO_RS09725 2126388..2126630 - 243 WP_035580249.1 type II toxin-antitoxin system ParD family antitoxin Antitoxin
HALO_RS09730 2126952..2130608 - 3657 WP_050713373.1 bifunctional proline dehydrogenase/L-glutamate gamma-semialdehyde dehydrogenase PutA -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(6-92)

Antitoxin

Antitoxin ParD

(4-71)


Sequences

Toxin        


Download         Length: 100 a.a.        Molecular weight: 11622.42 Da        Isoelectric Point: 10.3918

>T285571 WP_035580252.1 NZ_LN813019:c2126388-2126089 [Halomonas sp. R57-5]
MTLFTLTLAAKMDLRDIALFTQRRWGKKQRNVYLNQFDDSFWLLAETPDIGKSCDEIRQNYRKFPQGSHVIFYQQTGSHK
IRIIRILHKSMDVNAAFGA

Download         Length: 300 bp

Antitoxin


Download         Length: 81 a.a.        Molecular weight: 8978.83 Da        Isoelectric Point: 4.3988

>AT285571 WP_035580249.1 NZ_LN813019:c2126630-2126388 [Halomonas sp. R57-5]
MAKNTSITLGDHFENFVTTQVQSGRYGSTSEVIRSALRLLENQETKLHTLRQLLIEGEQSGDADYDLSSFINELDSEKSN

Download         Length: 243 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A0D6E807

Antitoxin

Source ID Structure
AlphaFold DB A0A0D6E7C4

References