Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) chpB-mazE/PRK09812-MazE
Location 921985..922591 Replicon chromosome
Accession NZ_LN794158
Organism Candidatus Methylopumilus turicensis strain MMS-10A-171

Toxin (Protein)


Gene name chpB Uniprot ID A0A0B7IUJ0
Locus tag BN1209_RS04640 Protein ID WP_045751162.1
Coordinates 921985..922326 (-) Length 114 a.a.

Antitoxin (Protein)


Gene name mazE Uniprot ID A0A0B7IZN7
Locus tag BN1209_RS04645 Protein ID WP_045751163.1
Coordinates 922343..922591 (-) Length 83 a.a.

Genomic Context

BN1209_RS04625BN1209_RS04630BN1209_RS04635BN1209_RS04655BN1209_RS04615BN1209_RS04640BN1209_RS04645BN1209_RS04650BN1209_RS09015BN1209_RS04660BN1209_RS04665
Location: 920579..920812 (234 bp)
Type: Others
Protein ID: WP_045751159.1
Location: 920885..921505 (621 bp)
Type: Others
Protein ID: WP_045751160.1
Location: 921492..921980 (489 bp)
Type: Others
Protein ID: WP_045751161.1
Location: 924809..926089 (1281 bp)
Type: Others
Protein ID: WP_045751165.1
Location: 918390..920207 (1818 bp)
Type: Others
Protein ID: WP_045751158.1
Location: 921985..922326 (342 bp)
Type: Toxin
Protein ID: WP_045751162.1
Location: 922343..922591 (249 bp)
Type: Antitoxin
Protein ID: WP_045751163.1
Location: 922646..924721 (2076 bp)
Type: Others
Protein ID: WP_045751164.1
Location: 926128..926418 (291 bp)
Type: Others
Protein ID: WP_082048394.1
Location: 926433..926849 (417 bp)
Type: Others
Protein ID: WP_045751166.1
Location: 926854..927183 (330 bp)
Type: Others
Protein ID: WP_045751167.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
BN1209_RS04615918390..920207-1818WP_045751158.1ABC transporter ATP-binding protein/permease-
BN1209_RS04625920579..920812+234WP_045751159.1VF530 family protein-
BN1209_RS04630920885..921505+621WP_045751160.1hypothetical protein-
BN1209_RS04635921492..921980+489WP_045751161.1hypothetical protein-
BN1209_RS04640921985..922326-342WP_045751162.1type II toxin-antitoxin system ChpB family toxinToxin
BN1209_RS04645922343..922591-249WP_045751163.1hypothetical proteinAntitoxin
BN1209_RS04650922646..924721-2076WP_045751164.1TonB-dependent receptor-
BN1209_RS04655924809..926089+1281WP_045751165.1divalent metal cation transporter-
BN1209_RS09015926128..926418-291WP_082048394.1hypothetical protein-
BN1209_RS04660926433..926849-417WP_045751166.1phage holin family protein-
BN1209_RS04665926854..927183-330WP_045751167.1DUF883 family protein-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase PemK-like

(5-112)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 114 a.a.        Molecular weight: 11956.78 Da        Isoelectric Point: 4.7718

>T285566 WP_045751162.1 NZ_LN794158:c922326-921985 [Candidatus Methylopumilus turicensis]
MAKFERGDVVRVCLNPTAGRETQGDFRPALVLSSAEVNDLGTAFIAPITQGGDFARFAGFAVSLTATGMETQGVVLVNML
RAVDLVARGAKKIEVAPAYVVEDALARLQAVFE

Download         Length: 342 bp

Antitoxin


Download         Length: 83 a.a.        Molecular weight: 8888.38 Da        Isoelectric Point: 10.1555

>AT285566 WP_045751163.1 NZ_LN794158:c922591-922343 [Candidatus Methylopumilus turicensis]
MKTVSIRKQGGAAIMTIPPDILKSLDAGVGSQLILKVQDGVFTATPIKSPPRKHYKLSDLLSQCDKNAPRNAEMAAWDNI
VQ

Download         Length: 249 bp


Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
AlphaFold DBA0A0B7IUJ0

Antitoxin

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Source
ID
Structure
AlphaFold DBA0A0B7IZN7

References