Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-YafN
Location 132844..133369 Replicon chromosome
Accession NZ_LN794158
Organism Candidatus Methylopumilus turicensis strain MMS-10A-171

Toxin (Protein)


Gene name relE Uniprot ID A0A0B7IXI4
Locus tag BN1209_RS00720 Protein ID WP_045750515.1
Coordinates 132844..133131 (-) Length 96 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID A0A0B7IXQ9
Locus tag BN1209_RS00725 Protein ID WP_045750516.1
Coordinates 133121..133369 (-) Length 83 a.a.

Genomic Context

BN1209_RS00700BN1209_RS00710BN1209_RS00740BN1209_RS00745BN1209_RS00750BN1209_RS00695BN1209_RS00705BN1209_RS00715BN1209_RS00720BN1209_RS00725BN1209_RS00730BN1209_RS00735
Location: 128921..130618 (1698 bp)
Type: Others
Protein ID: WP_045750511.1
Location: 131992..132453 (462 bp)
Type: Others
Protein ID: WP_045750513.1
Location: 135138..136574 (1437 bp)
Type: Others
Protein ID: WP_045750519.1
Location: 136596..137036 (441 bp)
Type: Others
Protein ID: WP_045751868.1
Location: 137038..137355 (318 bp)
Type: Others
Protein ID: WP_045751869.1
Location: 128153..128719 (567 bp)
Type: Others
Protein ID: WP_045750510.1
Location: 131170..131610 (441 bp)
Type: Others
Protein ID: WP_045750512.1
Location: 132521..132778 (258 bp)
Type: Others
Protein ID: WP_045750514.1
Location: 132844..133131 (288 bp)
Type: Toxin
Protein ID: WP_045750515.1
Location: 133121..133369 (249 bp)
Type: Antitoxin
Protein ID: WP_045750516.1
Location: 133495..134502 (1008 bp)
Type: Others
Protein ID: WP_045750517.1
Location: 134576..135049 (474 bp)
Type: Others
Protein ID: WP_045750518.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
BN1209_RS00695128153..128719-567WP_045750510.1site-specific integrase-
BN1209_RS00700128921..130618+1698WP_045750511.1hypothetical protein-
BN1209_RS00705131170..131610-441WP_045750512.1hypothetical protein-
BN1209_RS00710131992..132453+462WP_045750513.1hypothetical protein-
BN1209_RS00715132521..132778-258WP_045750514.1hypothetical protein-
BN1209_RS00720132844..133131-288WP_045750515.1type II toxin-antitoxin system RelE/ParE family toxinToxin
BN1209_RS00725133121..133369-249WP_045750516.1type II toxin-antitoxin system Phd/YefM family antitoxinAntitoxin
BN1209_RS00730133495..134502-1008WP_045750517.1site-specific integrase-
BN1209_RS00735134576..135049-474WP_045750518.1cyclic pyranopterin monophosphate synthase MoaC-
BN1209_RS00740135138..136574+1437WP_045750519.1M48 family metallopeptidase-
BN1209_RS00745136596..137036+441WP_045751868.1thiosulfate oxidation carrier protein SoxY-
BN1209_RS00750137038..137355+318WP_045751869.1thiosulfate oxidation carrier complex protein SoxZ-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(5-83)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(12-72)


Sequences

Toxin        


Download         Length: 96 a.a.        Molecular weight: 10966.79 Da        Isoelectric Point: 9.6740

>T285565 WP_045750515.1 NZ_LN794158:c133131-132844 [Candidatus Methylopumilus turicensis]
MIYELEFNEEALKEWNDLDGSIKAQFKKQLEKRLVNPHLPSARLGNDLEGCYKIKLQKIGYRLVYDVIDSRLVIIVLSVG
RRDGLAAYTKASKRI

Download         Length: 288 bp

Antitoxin


Download         Length: 83 a.a.        Molecular weight: 9071.42 Da        Isoelectric Point: 7.1991

>AT285565 WP_045750516.1 NZ_LN794158:c133369-133121 [Candidatus Methylopumilus turicensis]
MTITHKIYAPATVSMTDLRRASIADIVSDSPVAVLNHNKPAAYLLSANYYEALLDQVENIELSKIVRERRGGKTVKVSLD
DL

Download         Length: 249 bp


Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
AlphaFold DBA0A0B7IXI4

Antitoxin

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Source
ID
Structure
AlphaFold DBA0A0B7IXQ9

References