Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-YafN
Location 132844..133369 Replicon chromosome
Accession NZ_LN794158
Organism Candidatus Methylopumilus turicensis strain MMS-10A-171

Toxin (Protein)


Gene name relE Uniprot ID A0A0B7IXI4
Locus tag BN1209_RS00720 Protein ID WP_045750515.1
Coordinates 132844..133131 (-) Length 96 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID A0A0B7IXQ9
Locus tag BN1209_RS00725 Protein ID WP_045750516.1
Coordinates 133121..133369 (-) Length 83 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
BN1209_RS00695 128153..128719 - 567 WP_045750510.1 site-specific integrase -
BN1209_RS00700 128921..130618 + 1698 WP_045750511.1 hypothetical protein -
BN1209_RS00705 131170..131610 - 441 WP_045750512.1 hypothetical protein -
BN1209_RS00710 131992..132453 + 462 WP_045750513.1 hypothetical protein -
BN1209_RS00715 132521..132778 - 258 WP_045750514.1 hypothetical protein -
BN1209_RS00720 132844..133131 - 288 WP_045750515.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
BN1209_RS00725 133121..133369 - 249 WP_045750516.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
BN1209_RS00730 133495..134502 - 1008 WP_045750517.1 site-specific integrase -
BN1209_RS00735 134576..135049 - 474 WP_045750518.1 cyclic pyranopterin monophosphate synthase MoaC -
BN1209_RS00740 135138..136574 + 1437 WP_045750519.1 M48 family metallopeptidase -
BN1209_RS00745 136596..137036 + 441 WP_045751868.1 thiosulfate oxidation carrier protein SoxY -
BN1209_RS00750 137038..137355 + 318 WP_045751869.1 thiosulfate oxidation carrier complex protein SoxZ -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(5-83)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(12-72)


Sequences

Toxin        


Download         Length: 96 a.a.        Molecular weight: 10966.79 Da        Isoelectric Point: 9.6740

>T285565 WP_045750515.1 NZ_LN794158:c133131-132844 [Candidatus Methylopumilus turicensis]
MIYELEFNEEALKEWNDLDGSIKAQFKKQLEKRLVNPHLPSARLGNDLEGCYKIKLQKIGYRLVYDVIDSRLVIIVLSVG
RRDGLAAYTKASKRI

Download         Length: 288 bp

Antitoxin


Download         Length: 83 a.a.        Molecular weight: 9071.42 Da        Isoelectric Point: 7.1991

>AT285565 WP_045750516.1 NZ_LN794158:c133369-133121 [Candidatus Methylopumilus turicensis]
MTITHKIYAPATVSMTDLRRASIADIVSDSPVAVLNHNKPAAYLLSANYYEALLDQVENIELSKIVRERRGGKTVKVSLD
DL

Download         Length: 249 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A0B7IXI4

Antitoxin

Source ID Structure
AlphaFold DB A0A0B7IXQ9

References