Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RelB-YoeB
Location 3606774..3607279 Replicon chromosome
Accession NZ_LN681227
Organism Xenorhabdus nematophila AN6/1

Toxin (Protein)


Gene name relE Uniprot ID D3VB02
Locus tag XNC2_RS15785 Protein ID WP_013185276.1
Coordinates 3606774..3607028 (+) Length 85 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID D3VB03
Locus tag XNC2_RS15790 Protein ID WP_013185277.1
Coordinates 3607025..3607279 (+) Length 85 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
XNC2_RS15765 3603009..3603911 + 903 WP_113967468.1 Fe(3+) dicitrate ABC transporter substrate-binding protein FecB -
XNC2_RS15770 3603908..3604906 + 999 WP_013185273.1 iron-dicitrate ABC transporter permease FecC -
XNC2_RS15775 3604903..3605859 + 957 WP_013185274.1 Fe(3+) dicitrate ABC transporter permease subunit FecD -
XNC2_RS15780 3605860..3606630 + 771 WP_013185275.1 Fe(3+) dicitrate ABC transporter ATP-binding protein FecE -
XNC2_RS15785 3606774..3607028 + 255 WP_013185276.1 type II toxin-antitoxin system prevent-host-death family antitoxin Toxin
XNC2_RS15790 3607025..3607279 + 255 WP_013185277.1 Txe/YoeB family addiction module toxin Antitoxin
XNC2_RS15795 3607399..3608676 - 1278 WP_013185278.1 coenzyme F390 synthetase -
XNC2_RS15800 3608673..3609479 - 807 WP_013185279.1 MBL fold metallo-hydrolase -
XNC2_RS15805 3609472..3610491 - 1020 WP_013185280.1 NAD(P)-dependent oxidoreductase -
XNC2_RS15810 3610488..3611486 - 999 WP_013185281.1 ketoacyl-ACP synthase III -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-74)

Antitoxin

Toxin YoeB

(5-84)


Sequences

Toxin        


Download         Length: 85 a.a.        Molecular weight: 9511.78 Da        Isoelectric Point: 5.0893

>T285557 WP_013185276.1 NZ_LN681227:3606774-3607028 [Xenorhabdus nematophila AN6/1]
MNVMSYSAFRTHLAKTLDKVNDDHQPVMITRQNGKPAVVLSLEDFRAYEETAYLMASPKNATRLNQAIAEVENGKTLEKD
LLEE

Download         Length: 255 bp

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 10245.67 Da        Isoelectric Point: 8.8345

>AT285557 WP_013185277.1 NZ_LN681227:3607025-3607279 [Xenorhabdus nematophila AN6/1]
MILSWAETAWEDYLYWQQTDKKTLKRINTLIKDIARQSFDGLGDPEPLKHNWSGYWSRRIDREHRLVYKVTDTAIIIVQC
RYHY

Download         Length: 255 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB D3VB02

Antitoxin

Source ID Structure
AlphaFold DB D3VB03

References