Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) ccdAB/CcdA(antitoxin)
Location 82779..83325 Replicon chromosome
Accession NZ_LN681227
Organism Xenorhabdus nematophila AN6/1

Toxin (Protein)


Gene name ccdB Uniprot ID N1NNP2
Locus tag XNC2_RS00375 Protein ID WP_010847542.1
Coordinates 83020..83325 (+) Length 102 a.a.

Antitoxin (Protein)


Gene name ccdA Uniprot ID -
Locus tag XNC2_RS00370 Protein ID WP_173363083.1
Coordinates 82779..83018 (+) Length 80 a.a.

Genomic Context

XNC2_RS00350XNC2_RS00360XNC2_RS00365XNC2_RS00370XNC2_RS00375XNC2_RS20950XNC2_RS00345XNC2_RS00355XNC2_RS00380XNC2_RS00385
Location: 80397..81161 (765 bp)
Type: Others
Protein ID: WP_013183068.1
Location: 82146..82346 (201 bp)
Type: Others
Protein ID: Protein_67
Location: 82355..82696 (342 bp)
Type: Others
Protein ID: WP_081480159.1
Location: 82779..83018 (240 bp)
Type: Antitoxin
Protein ID: WP_173363083.1
Location: 83020..83325 (306 bp)
Type: Toxin
Protein ID: WP_010847542.1
Location: 85743..86051 (309 bp)
Type: Others
Protein ID: WP_010847546.1
Location: 79024..79764 (741 bp)
Type: Others
Protein ID: WP_010847535.1
Location: 81167..81997 (831 bp)
Type: Others
Protein ID: WP_013183069.1
Location: 83428..85506 (2079 bp)
Type: Others
Protein ID: WP_013183074.1
Location: 85490..85705 (216 bp)
Type: Others
Protein ID: WP_010847545.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
XNC2_RS0034579024..79764-741WP_010847535.1transferrin-binding protein-like solute binding protein-
XNC2_RS0035080397..81161+765WP_013183068.1hypothetical protein-
XNC2_RS0035581167..81997-831WP_013183069.1formate dehydrogenase accessory sulfurtransferase FdhD-
XNC2_RS0036082146..82346+201Protein_67hypothetical protein-
XNC2_RS0036582355..82696+342WP_081480159.1formate dehydrogenase subunit gamma-
XNC2_RS0037082779..83018+240WP_173363083.1type II toxin-antitoxin system CcdA family antitoxinAntitoxin
XNC2_RS0037583020..83325+306WP_010847542.1CcdB family proteinToxin
XNC2_RS0038083428..85506-2079WP_013183074.1plasmid pRiA4b ORF-3 family protein-
XNC2_RS0038585490..85705-216WP_010847545.1hypothetical protein-
XNC2_RS2095085743..86051+309WP_010847546.1formate dehydrogenase accessory protein FdhE-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin CcdB

(2-100)

Antitoxin

Post-segregation antitoxin CcdA

(9-79)


Sequences

Toxin        


Download         Length: 102 a.a.        Molecular weight: 11543.30 Da        Isoelectric Point: 4.9756

>T285545 WP_010847542.1 NZ_LN681227:83020-83325 [Xenorhabdus nematophila AN6/1]
MQYTVYKNTGNPDYSYLLDVQSDIIDVLETRLVIPLFLKSNFHGRIPTRLCPTLNIDGNEYLVMTHAMASIRVSMLGDEM
TNVSSHRQLIKDAMDLLFDGF

Download         Length: 306 bp

Antitoxin


Download         Length: 80 a.a.        Molecular weight: 9037.22 Da        Isoelectric Point: 8.5906

>AT285545 WP_173363083.1 NZ_LN681227:82779-83018 [Xenorhabdus nematophila AN6/1]
MTALHSRTKKTVSVTVSPELYEQAKQIGLNFSAILTQALIAELKSAAAEQWKRDNREGFEELNRITREHGLLSDQYRTF

Download         Length: 240 bp


Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
AlphaFold DBN1NNP2

Antitoxin

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Source
ID
Structure
No matching records found

References