Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) ccdAB/CcdA(antitoxin)
Location 82779..83325 Replicon chromosome
Accession NZ_LN681227
Organism Xenorhabdus nematophila AN6/1

Toxin (Protein)


Gene name ccdB Uniprot ID N1NNP2
Locus tag XNC2_RS00375 Protein ID WP_010847542.1
Coordinates 83020..83325 (+) Length 102 a.a.

Antitoxin (Protein)


Gene name ccdA Uniprot ID -
Locus tag XNC2_RS00370 Protein ID WP_173363083.1
Coordinates 82779..83018 (+) Length 80 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
XNC2_RS00345 79024..79764 - 741 WP_010847535.1 transferrin-binding protein-like solute binding protein -
XNC2_RS00350 80397..81161 + 765 WP_013183068.1 hypothetical protein -
XNC2_RS00355 81167..81997 - 831 WP_013183069.1 formate dehydrogenase accessory sulfurtransferase FdhD -
XNC2_RS00360 82146..82346 + 201 Protein_67 hypothetical protein -
XNC2_RS00365 82355..82696 + 342 WP_081480159.1 formate dehydrogenase subunit gamma -
XNC2_RS00370 82779..83018 + 240 WP_173363083.1 type II toxin-antitoxin system CcdA family antitoxin Antitoxin
XNC2_RS00375 83020..83325 + 306 WP_010847542.1 CcdB family protein Toxin
XNC2_RS00380 83428..85506 - 2079 WP_013183074.1 plasmid pRiA4b ORF-3 family protein -
XNC2_RS00385 85490..85705 - 216 WP_010847545.1 hypothetical protein -
XNC2_RS20950 85743..86051 + 309 WP_010847546.1 formate dehydrogenase accessory protein FdhE -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin CcdB

(2-100)

Antitoxin

Post-segregation antitoxin CcdA

(9-79)


Sequences

Toxin        


Download         Length: 102 a.a.        Molecular weight: 11543.30 Da        Isoelectric Point: 4.9756

>T285545 WP_010847542.1 NZ_LN681227:83020-83325 [Xenorhabdus nematophila AN6/1]
MQYTVYKNTGNPDYSYLLDVQSDIIDVLETRLVIPLFLKSNFHGRIPTRLCPTLNIDGNEYLVMTHAMASIRVSMLGDEM
TNVSSHRQLIKDAMDLLFDGF

Download         Length: 306 bp

Antitoxin


Download         Length: 80 a.a.        Molecular weight: 9037.22 Da        Isoelectric Point: 8.5906

>AT285545 WP_173363083.1 NZ_LN681227:82779-83018 [Xenorhabdus nematophila AN6/1]
MTALHSRTKKTVSVTVSPELYEQAKQIGLNFSAILTQALIAELKSAAAEQWKRDNREGFEELNRITREHGLLSDQYRTF

Download         Length: 240 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB N1NNP2

Antitoxin

Source ID Structure

References