Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) tad-ata/COG5606-COG4679
Location 5019090..5019751 Replicon chromosome
Accession NC_019748
Organism Stanieria cyanosphaera PCC 7437

Toxin (Protein)


Gene name tad Uniprot ID -
Locus tag STA7437_RS22000 Protein ID WP_150109180.1
Coordinates 5019090..5019416 (+) Length 109 a.a.

Antitoxin (Protein)


Gene name ata Uniprot ID K9XZI1
Locus tag STA7437_RS22005 Protein ID WP_015195592.1
Coordinates 5019416..5019751 (+) Length 112 a.a.

Genomic Context

STA7437_RS21980STA7437_RS21985STA7437_RS21990STA7437_RS21995STA7437_RS22000STA7437_RS22005STA7437_RS22010STA7437_RS25130STA7437_RS22020STA7437_RS22025
Location: 5014230..5014613 (384 bp)
Type: Others
Protein ID: WP_015195587.1
Location: 5014889..5015068 (180 bp)
Type: Others
Protein ID: WP_015195588.1
Location: 5015236..5016072 (837 bp)
Type: Others
Protein ID: WP_015195589.1
Location: 5016346..5018946 (2601 bp)
Type: Others
Protein ID: WP_015195590.1
Location: 5019090..5019416 (327 bp)
Type: Toxin
Protein ID: WP_150109180.1
Location: 5019416..5019751 (336 bp)
Type: Antitoxin
Protein ID: WP_015195592.1
Location: 5019810..5020592 (783 bp)
Type: Others
Protein ID: WP_015195593.1
Location: 5020652..5021071 (420 bp)
Type: Others
Protein ID: WP_015195594.1
Location: 5021234..5023180 (1947 bp)
Type: Others
Protein ID: WP_015195595.1
Location: 5023340..5024002 (663 bp)
Type: Others
Protein ID: WP_015195596.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
STA7437_RS219805014230..5014613+384WP_015195587.1hypothetical protein-
STA7437_RS219855014889..5015068+180WP_015195588.1hypothetical protein-
STA7437_RS219905015236..5016072+837WP_015195589.1hypothetical protein-
STA7437_RS219955016346..5018946+2601WP_015195590.1CHAT domain-containing protein-
STA7437_RS220005019090..5019416+327WP_150109180.1type II toxin-antitoxin system RelE/ParE family toxinToxin
STA7437_RS220055019416..5019751+336WP_015195592.1helix-turn-helix domain-containing proteinAntitoxin
STA7437_RS220105019810..5020592-783WP_015195593.1DUF928 domain-containing protein-
STA7437_RS251305020652..5021071-420WP_015195594.1hypothetical protein-
STA7437_RS220205021234..5023180-1947WP_015195595.1CHASE2 domain-containing protein-
STA7437_RS220255023340..5024002-663WP_015195596.1response regulator transcription factor-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-like

(8-98)

Antitoxin

HigA2-like, helix-turn-helix domain

(17-95)


Sequences

Toxin        


Download         Length: 109 a.a.        Molecular weight: 12095.85 Da        Isoelectric Point: 10.1015

>T28554 WP_150109180.1 NC_019748:5019090-5019416 [Stanieria cyanosphaera PCC 7437]
MGDSLKQVKSFPDAVRRDIGSSLYDAQKGDKPDNAKPLKGVGNGIFEIVTRFDSDTYRTVYAIQIGNCIYVLHAFQKKSP
KGIKTAQKDVDLIKKRYKQALEISKESN

Download         Length: 327 bp

>T28554 NC_019748:5019090-5019416 [Stanieria cyanosphaera PCC 7437]
ATGGGAGATAGCCTCAAACAAGTCAAAAGCTTCCCAGATGCTGTACGTCGTGATATTGGTTCATCTCTGTATGATGCACA
AAAAGGAGATAAACCAGACAACGCCAAGCCTCTTAAGGGAGTAGGCAATGGAATTTTTGAGATTGTTACACGATTTGACT
CTGATACCTACAGGACGGTTTACGCGATACAAATTGGAAACTGCATTTATGTCCTTCATGCTTTTCAGAAAAAATCGCCC
AAGGGTATAAAGACGGCACAGAAAGATGTCGATTTAATTAAAAAACGTTATAAGCAAGCACTTGAGATCTCGAAGGAGTC
AAACTAA

Antitoxin


Download         Length: 112 a.a.        Molecular weight: 12850.82 Da        Isoelectric Point: 5.6927

>AT28554 WP_015195592.1 NC_019748:5019416-5019751 [Stanieria cyanosphaera PCC 7437]
MSEENTPIEFIKSSGNVFEDLDLEDAEELLIRAKLGYTVRQILESRHLKQQEIATLLKIKQPEVSNLMKGKYHLFSEGRL
FGFLNKLEQKIIIQIAQHRTGEPLQDVTLEK

Download         Length: 336 bp

>AT28554 NC_019748:5019416-5019751 [Stanieria cyanosphaera PCC 7437]
ATGAGTGAAGAAAACACGCCAATCGAATTTATCAAAAGTAGTGGCAATGTTTTTGAAGATCTGGACTTAGAAGACGCAGA
AGAACTATTGATTCGTGCCAAACTGGGTTATACTGTCCGCCAAATATTAGAAAGTCGTCATTTAAAACAGCAAGAAATTG
CGACTCTTTTGAAGATTAAACAACCAGAAGTATCTAACCTAATGAAAGGTAAGTATCATCTATTTTCTGAAGGTCGCTTA
TTTGGTTTCCTAAATAAACTGGAACAAAAAATAATTATTCAAATTGCTCAACATCGTACTGGAGAACCATTACAAGATGT
TACTTTAGAAAAGTAA

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
No matching records found

Antitoxin

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Source
ID
Structure
AlphaFold DBK9XZI1

References