28551

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PP_4151-4152/excise(antitoxin)
Location 3944189..3945238 Replicon chromosome
Accession NC_019748
Organism Stanieria cyanosphaera PCC 7437

Toxin (Protein)


Gene name PP_4152 Uniprot ID -
Locus tag STA7437_RS17140 Protein ID WP_015194651.1
Coordinates 3944189..3944758 (-) Length 190 a.a.

Antitoxin (Protein)


Gene name PP_4151 Uniprot ID -
Locus tag STA7437_RS17145 Protein ID WP_150109086.1
Coordinates 3944765..3945238 (-) Length 158 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
STA7437_RS17120 3939373..3939645 + 273 WP_051036070.1 type II toxin-antitoxin system death-on-curing family toxin -
STA7437_RS17125 3939816..3943583 + 3768 WP_015194648.1 magnesium chelatase subunit H -
STA7437_RS17130 3943605..3943808 + 204 WP_015194649.1 type II toxin-antitoxin system HicA family toxin -
STA7437_RS17135 3943810..3944022 + 213 WP_015194650.1 type II toxin-antitoxin system HicB family antitoxin -
STA7437_RS17140 3944189..3944758 - 570 WP_015194651.1 PIN domain-containing protein Toxin
STA7437_RS17145 3944765..3945238 - 474 WP_150109086.1 helix-turn-helix domain-containing protein Antitoxin
STA7437_RS17150 3945460..3946299 + 840 WP_015194653.1 alpha/beta fold hydrolase -
STA7437_RS17155 3946357..3946809 + 453 WP_015194654.1 photosystem II protein PsbQ -
STA7437_RS17160 3947000..3948094 + 1095 WP_015194655.1 FAD-binding oxidoreductase -
STA7437_RS17165 3948138..3948902 + 765 WP_015194656.1 YebC/PmpR family DNA-binding transcriptional regulator -
STA7437_RS17170 3949266..3949762 - 497 Protein_3455 DUF3368 domain-containing protein -
STA7437_RS17175 3949759..3950004 - 246 WP_015194657.1 UPF0175 family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(6-112)

Antitoxin

SinI-like, DNA-binding domain

(87-132)


Sequences

Toxin        


Download         Length: 190 a.a.        Molecular weight: 21999.49 Da        Isoelectric Point: 7.6629

>T28551 WP_015194651.1 NC_019748:c3944758-3944189 [Stanieria cyanosphaera PCC 7437]
VSNFTVIYDSCVLYLAPLRDFLMELALTDLFKARWTNQIHDEWISNLLKNRPDLTLERLIRTRDLMNARVRDCLVIGYEE
LIPGLRLPDPGDRHILAAAIRCKADVIVTFNLSDFPYNYLATYRIEAQHPDEFIRHLVDLNRAAVCLAAKQQRLRLKNPP
KTRNEYLNTLLNQGLPQTKAALQEFCYEL

Download         Length: 570 bp

>T28551 NC_019748:c3944758-3944189 [Stanieria cyanosphaera PCC 7437]
GTGTCAAATTTTACCGTTATTTACGATTCGTGTGTACTATACCTTGCTCCATTAAGAGATTTCTTGATGGAGCTTGCGCT
TACAGATTTGTTTAAAGCGCGTTGGACAAATCAAATTCATGATGAATGGATTAGTAATCTTCTGAAAAATCGTCCAGATC
TTACGTTGGAACGACTTATTAGAACCAGAGATTTAATGAATGCAAGGGTTAGAGACTGTCTCGTGATAGGTTATGAAGAA
CTAATCCCAGGATTGCGACTACCCGATCCAGGCGATCGCCATATTCTAGCAGCAGCAATTCGTTGTAAAGCCGATGTGAT
TGTCACTTTTAACTTAAGTGATTTTCCATATAATTATCTAGCAACATATAGAATTGAAGCTCAACATCCAGATGAATTTA
TTCGGCATTTAGTAGATTTAAATCGAGCAGCAGTATGCTTGGCAGCAAAACAGCAGAGACTTAGACTTAAAAATCCACCT
AAAACACGAAATGAATACTTAAACACACTTTTAAATCAAGGTCTTCCTCAAACTAAAGCTGCATTGCAGGAGTTTTGTTA
TGAACTTTAG

Antitoxin


Download         Length: 158 a.a.        Molecular weight: 17725.59 Da        Isoelectric Point: 5.9743

>AT28551 WP_150109086.1 NC_019748:c3945238-3944765 [Stanieria cyanosphaera PCC 7437]
MRRLISMTMKMLPTEEEATLAKASSRKIASYLVKSSPVQNIALIQDDINQKSEAIAIPTEALRLLIDILTQMAQGNAVTL
IPIHAELTTQEAADILNVSRPYLVGLLEAGEIPFRKVGTRRRVRYQDLKDYKDKIDTERRKILDELVAEAQELDMGY

Download         Length: 474 bp

>AT28551 NC_019748:c3945238-3944765 [Stanieria cyanosphaera PCC 7437]
ATGAGAAGGTTAATTTCCATGACAATGAAAATGTTACCGACAGAAGAAGAAGCTACATTAGCTAAAGCTAGTAGTAGAAA
AATTGCTTCCTATCTAGTTAAAAGCTCTCCTGTCCAAAATATTGCTCTTATCCAAGATGATATCAATCAAAAAAGTGAAG
CGATCGCAATCCCTACAGAAGCACTTCGCTTATTGATTGACATTTTGACACAAATGGCTCAGGGAAATGCAGTAACGTTA
ATACCCATTCACGCGGAATTAACTACTCAAGAAGCTGCTGATATTTTAAATGTATCTCGTCCTTATTTAGTTGGGTTACT
CGAAGCAGGAGAAATACCTTTTCGGAAAGTAGGAACACGTCGTCGAGTACGTTATCAAGACTTAAAAGATTACAAAGATA
AAATTGATACGGAAAGGAGAAAAATTCTTGATGAACTCGTTGCTGAAGCGCAAGAATTAGATATGGGATATTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References