Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) prpT-prpA/ParE-CC2985
Location 140492..141032 Replicon plasmid II
Accession NZ_LN614828
Organism Legionella fallonii LLAP-10

Toxin (Protein)


Gene name PrpT Uniprot ID A0A098G9U2
Locus tag LFA_RS18090 Protein ID WP_045097841.1
Coordinates 140492..140788 (-) Length 99 a.a.

Antitoxin (Protein)


Gene name PrpA Uniprot ID A0A098GB99
Locus tag LFA_RS18095 Protein ID WP_045097842.1
Coordinates 140778..141032 (-) Length 85 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LFA_RS18065 135598..135888 + 291 WP_045097837.1 helix-turn-helix domain-containing protein -
LFA_RS18070 135982..136311 + 330 WP_045097838.1 hypothetical protein -
LFA_RS18075 136696..137076 - 381 WP_045097951.1 nucleoside triphosphate hydrolase -
LFA_RS18080 137230..138732 + 1503 WP_045097839.1 DUF3987 domain-containing protein -
LFA_RS18085 139055..140362 + 1308 WP_045097840.1 hypothetical protein -
LFA_RS18090 140492..140788 - 297 WP_045097841.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
LFA_RS18095 140778..141032 - 255 WP_045097842.1 type II toxin-antitoxin system ParD family antitoxin Antitoxin
LFA_RS18100 141250..142299 - 1050 WP_045097843.1 tyrosine-type recombinase/integrase -
LFA_RS18105 142456..143004 + 549 WP_045097844.1 ORF6N domain-containing protein -
LFA_RS18115 143129..144216 + 1088 WP_157010461.1 IS3 family transposase -
LFA_RS18120 144209..144553 + 345 WP_045097846.1 hypothetical protein -
LFA_RS19120 144675..145133 + 459 WP_157010465.1 DUF4156 domain-containing protein -
LFA_RS18130 145172..145393 - 222 Protein_138 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..238761 238761


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(6-94)

Antitoxin

Antitoxin ParD

(1-78)


Sequences

Toxin        


Download         Length: 99 a.a.        Molecular weight: 11765.52 Da        Isoelectric Point: 7.3524

>T285484 WP_045097841.1 NZ_LN614828:c140788-140492 [Legionella fallonii LLAP-10]
MPNKTYRLYPKAIEDLESIYLYSMREFGIKRTEDYILTIETSFQYLADDPLISRTCDYVRQDLRAFNVGSHVIFFKMTHY
GIAVIRVLHQSMDFNRHF

Download         Length: 297 bp

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 9766.03 Da        Isoelectric Point: 4.9001

>AT285484 WP_045097842.1 NZ_LN614828:c141032-140778 [Legionella fallonii LLAP-10]
MARTMTVDLGSELRDYVQFLVDSGDYRSNSEVLRESLRLLREKQAESKLEQLRHLIDEGEGSGDPLMWNAEEFLDRMKKV
PHAK

Download         Length: 255 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A098G9U2

Antitoxin

Source ID Structure
AlphaFold DB A0A098GB99

References