Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) rlegTA/AbiEii-AbiEi
Location 3596604..3598072 Replicon chromosome
Accession NZ_LN614827
Organism Legionella fallonii LLAP-10

Toxin (Protein)


Gene name rlegT Uniprot ID A0A098GAU5
Locus tag LFA_RS14990 Protein ID WP_045096892.1
Coordinates 3596604..3597467 (-) Length 288 a.a.

Antitoxin (Protein)


Gene name rlegA Uniprot ID -
Locus tag LFA_RS14995 Protein ID WP_045097665.1
Coordinates 3597464..3598072 (-) Length 203 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LFA_RS14980 3593873..3595576 + 1704 WP_045096891.1 acyl--CoA ligase -
LFA_RS14985 3595598..3596305 + 708 WP_197541193.1 hypothetical protein -
LFA_RS14990 3596604..3597467 - 864 WP_045096892.1 nucleotidyl transferase AbiEii/AbiGii toxin family protein Toxin
LFA_RS14995 3597464..3598072 - 609 WP_045097665.1 AbiEi antitoxin N-terminal domain-containing protein Antitoxin
LFA_RS15000 3598431..3598700 - 270 WP_045096893.1 hypothetical protein -
LFA_RS15005 3598900..3600354 + 1455 WP_052673996.1 hypothetical protein -
LFA_RS15010 3601353..3602474 + 1122 WP_045096894.1 hypothetical protein -
LFA_RS20195 3602449..3602631 - 183 WP_197541194.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Nucleotidyl transferase AbiEii toxin, Type IV TA system

(35-259)

Antitoxin

Transcriptional regulator, AbiEi antitoxin

(9-56)


Sequences

Toxin        


Download         Length: 288 a.a.        Molecular weight: 32098.04 Da        Isoelectric Point: 6.7355

>T285483 WP_045096892.1 NZ_LN614827:c3597467-3596604 [Legionella fallonii LLAP-10]
MTKNIGESVRSRLKNIAVKEGSDFNAVLTRYGLERLLYRIGESEYSKQFLLKGALLFNLWYDMPHRPTKDIDLLGFGDND
LAYIKQTFSKICRISADDGISFLSESVTVDTIKKDGGYTGARVELFGELAKAKIKIQIDIGYGDAVTPGPIDAHYPVLLS
DLPAPKIRTYPIYTVIAEKLHAIALLGMANSRLKDYLDLYVLLNNEQIDNQILAEAIQATFTRRGMILPEALPIGLTDEF
ANDPSRESMWKAFLRKNELEQRSLVEVISRISTLIQSSMSLATKAVS

Download         Length: 864 bp

Antitoxin


Download         Length: 203 a.a.        Molecular weight: 23001.88 Da        Isoelectric Point: 8.7512

>AT285483 WP_045097665.1 NZ_LN614827:c3598072-3597464 [Legionella fallonii LLAP-10]
MKTEDSYKQKVLQMASKTGVIRMSDLTKEGITRATISRLVSENKLEKLASGLYCLPETELSEKESLIIIASRVPQAVFCL
LTALQIHDLTTQLPRKVWIAMPKGSHVPKMDYPPLKMVQYSDEAFSEGIEIIESDNIKLRVYNRAKTIADCFKHRNKIGL
DVAIEALKEAYTKNQVTVDELWHYAKICRVANVMRPYIEAIQ

Download         Length: 609 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A098GAU5

Antitoxin

Source ID Structure

References