Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | mazEF/PRK09907-MazE |
| Location | 95560..96130 | Replicon | chromosome |
| Accession | NC_019748 | ||
| Organism | Stanieria cyanosphaera PCC 7437 | ||
Toxin (Protein)
| Gene name | mazF | Uniprot ID | K9XMI9 |
| Locus tag | STA7437_RS00415 | Protein ID | WP_015191381.1 |
| Coordinates | 95780..96130 (+) | Length | 117 a.a. |
Antitoxin (Protein)
| Gene name | mazE | Uniprot ID | K9XPV3 |
| Locus tag | STA7437_RS00410 | Protein ID | WP_015191380.1 |
| Coordinates | 95560..95799 (+) | Length | 80 a.a. |
Genomic Context
Location: 91193..92176 (984 bp)
Type: Others
Protein ID: WP_015191376.1
Type: Others
Protein ID: WP_015191376.1
Location: 92397..94046 (1650 bp)
Type: Others
Protein ID: WP_015191377.1
Type: Others
Protein ID: WP_015191377.1
Location: 95560..95799 (240 bp)
Type: Antitoxin
Protein ID: WP_015191380.1
Type: Antitoxin
Protein ID: WP_015191380.1
Location: 95780..96130 (351 bp)
Type: Toxin
Protein ID: WP_015191381.1
Type: Toxin
Protein ID: WP_015191381.1
Location: 99624..100130 (507 bp)
Type: Others
Protein ID: WP_150109097.1
Type: Others
Protein ID: WP_150109097.1
Location: 94344..95177 (834 bp)
Type: Others
Protein ID: WP_015191378.1
Type: Others
Protein ID: WP_015191378.1
Location: 95248..95514 (267 bp)
Type: Others
Protein ID: WP_015191379.1
Type: Others
Protein ID: WP_015191379.1
Location: 96265..97533 (1269 bp)
Type: Others
Protein ID: WP_015191382.1
Type: Others
Protein ID: WP_015191382.1
Location: 97648..99195 (1548 bp)
Type: Others
Protein ID: WP_015191383.1
Type: Others
Protein ID: WP_015191383.1
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Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| STA7437_RS00390 | 91193..92176 | + | 984 | WP_015191376.1 | RNA polymerase sigma factor, RpoD/SigA family | - |
| STA7437_RS00395 | 92397..94046 | + | 1650 | WP_015191377.1 | aminotransferase class I/II-fold pyridoxal phosphate-dependent enzyme | - |
| STA7437_RS00400 | 94344..95177 | - | 834 | WP_015191378.1 | aldo/keto reductase | - |
| STA7437_RS00405 | 95248..95514 | - | 267 | WP_015191379.1 | hypothetical protein | - |
| STA7437_RS00410 | 95560..95799 | + | 240 | WP_015191380.1 | AbrB/MazE/SpoVT family DNA-binding domain-containing protein | Antitoxin |
| STA7437_RS00415 | 95780..96130 | + | 351 | WP_015191381.1 | type II toxin-antitoxin system PemK/MazF family toxin | Toxin |
| STA7437_RS00420 | 96265..97533 | - | 1269 | WP_015191382.1 | bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase CoaBC | - |
| STA7437_RS00425 | 97648..99195 | - | 1548 | WP_015191383.1 | B12-binding domain-containing radical SAM protein | - |
| STA7437_RS00430 | 99624..100130 | + | 507 | WP_150109097.1 | N-acetyltransferase | - |
Associated MGEs
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MGE detail | Similar MGEs | Relative position | MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| No matching records found | |||||||
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 117 a.a. Molecular weight: 13075.45 Da Isoelectric Point: 10.3846
>T28548 WP_015191381.1 NC_019748:95780-96130 [Stanieria cyanosphaera PCC 7437]
VKKSGSKQYIPDRGDIIWLDFNPQIGREQAGHRPAIVISPKKFNSLSSLVFVCPISSKIKGFSFEVLLTEQMQTKGVVLI
HHLRSVDWKTRGIKFVETAPISIVEEICAKLKPLIF
VKKSGSKQYIPDRGDIIWLDFNPQIGREQAGHRPAIVISPKKFNSLSSLVFVCPISSKIKGFSFEVLLTEQMQTKGVVLI
HHLRSVDWKTRGIKFVETAPISIVEEICAKLKPLIF
Download Length: 351 bp
>T28548 NC_019748:95780-96130 [Stanieria cyanosphaera PCC 7437]
GTGAAGAAATCTGGGAGTAAACAATATATTCCGGACAGAGGCGATATTATTTGGCTAGATTTCAATCCTCAGATCGGACG
TGAGCAAGCGGGACATCGCCCTGCTATTGTTATATCTCCGAAAAAGTTTAATTCTCTTTCTTCTCTGGTTTTTGTCTGTC
CGATTAGTAGCAAAATTAAGGGATTTAGTTTTGAAGTTTTATTAACTGAACAGATGCAAACTAAAGGAGTTGTTTTAATT
CATCACCTCAGAAGCGTTGACTGGAAAACTAGAGGAATTAAATTTGTGGAAACAGCACCTATCTCAATAGTTGAAGAAAT
ATGTGCCAAGTTAAAGCCATTAATTTTCTAA
GTGAAGAAATCTGGGAGTAAACAATATATTCCGGACAGAGGCGATATTATTTGGCTAGATTTCAATCCTCAGATCGGACG
TGAGCAAGCGGGACATCGCCCTGCTATTGTTATATCTCCGAAAAAGTTTAATTCTCTTTCTTCTCTGGTTTTTGTCTGTC
CGATTAGTAGCAAAATTAAGGGATTTAGTTTTGAAGTTTTATTAACTGAACAGATGCAAACTAAAGGAGTTGTTTTAATT
CATCACCTCAGAAGCGTTGACTGGAAAACTAGAGGAATTAAATTTGTGGAAACAGCACCTATCTCAATAGTTGAAGAAAT
ATGTGCCAAGTTAAAGCCATTAATTTTCTAA
Antitoxin
Download Length: 80 a.a. Molecular weight: 8750.74 Da Isoelectric Point: 3.8960
>AT28548 WP_015191380.1 NC_019748:95560-95799 [Stanieria cyanosphaera PCC 7437]
MSTVAKWGNSLAIRIPKNIADKINLKEGTAISIDVTDTNIVITPKQPNYTLEELLAGANSEDFEGEYDWGEPVGEEIWE
MSTVAKWGNSLAIRIPKNIADKINLKEGTAISIDVTDTNIVITPKQPNYTLEELLAGANSEDFEGEYDWGEPVGEEIWE
Download Length: 240 bp
>AT28548 NC_019748:95560-95799 [Stanieria cyanosphaera PCC 7437]
ATGTCAACAGTAGCCAAATGGGGAAATAGTCTAGCGATACGCATTCCCAAAAATATTGCCGACAAAATTAATTTAAAAGA
AGGAACTGCTATTTCTATTGATGTTACTGATACCAACATTGTCATTACTCCCAAACAACCGAACTACACCCTTGAAGAAT
TACTCGCTGGAGCAAATAGTGAAGACTTTGAAGGAGAATATGATTGGGGAGAGCCAGTAGGTGAAGAAATCTGGGAGTAA
ATGTCAACAGTAGCCAAATGGGGAAATAGTCTAGCGATACGCATTCCCAAAAATATTGCCGACAAAATTAATTTAAAAGA
AGGAACTGCTATTTCTATTGATGTTACTGATACCAACATTGTCATTACTCCCAAACAACCGAACTACACCCTTGAAGAAT
TACTCGCTGGAGCAAATAGTGAAGACTTTGAAGGAGAATATGATTGGGGAGAGCCAGTAGGTGAAGAAATCTGGGAGTAA