285463

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/LOTUS_5_Limkain_b1-VagC
Location 2336230..2336909 Replicon chromosome
Accession NZ_LN606600
Organism Acetobacter senegalensis strain 108B

Toxin (Protein)


Gene name vapC Uniprot ID A0A5B9GMW7
Locus tag ASN_RS10885 Protein ID WP_058988177.1
Coordinates 2336499..2336909 (+) Length 137 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag ASN_RS10880 Protein ID WP_058988176.1
Coordinates 2336230..2336502 (+) Length 91 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
ASN_RS10850 2332855..2333535 + 681 WP_058988170.1 hypothetical protein -
ASN_RS10855 2333595..2333894 + 300 WP_058988171.1 hypothetical protein -
ASN_RS19965 2333887..2334033 + 147 WP_162870764.1 hypothetical protein -
ASN_RS10865 2334756..2335244 + 489 WP_058988173.1 single-stranded DNA-binding protein -
ASN_RS10870 2335307..2335744 + 438 WP_058988174.1 hypothetical protein -
ASN_RS10875 2335741..2336157 + 417 WP_058988175.1 hypothetical protein -
ASN_RS10880 2336230..2336502 + 273 WP_058988176.1 AbrB/MazE/SpoVT family DNA-binding domain-containing protein Antitoxin
ASN_RS10885 2336499..2336909 + 411 WP_058988177.1 type II toxin-antitoxin system VapC family toxin Toxin
ASN_RS10890 2336978..2337511 + 534 WP_058988178.1 hypothetical protein -
ASN_RS10895 2337508..2337708 + 201 WP_006560470.1 hypothetical protein -
ASN_RS18830 2337836..2338048 + 213 WP_082666815.1 hypothetical protein -
ASN_RS10900 2338143..2338535 - 393 WP_058988179.1 hypothetical protein -
ASN_RS10905 2338547..2339359 - 813 WP_058988180.1 hypothetical protein -
ASN_RS10910 2339456..2339920 - 465 WP_058988181.1 hypothetical protein -
ASN_RS10915 2339923..2340771 - 849 WP_058988182.1 hypothetical protein -
ASN_RS10920 2340888..2341709 - 822 WP_099048371.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(4-123)

Antitoxin

SpoVT-AbrB domain

(16-54)


Sequences

Toxin        


Download         Length: 137 a.a.        Molecular weight: 14787.09 Da        Isoelectric Point: 5.2057

>T285463 WP_058988177.1 NZ_LN606600:2336499-2336909 [Acetobacter senegalensis]
VSAYLLDTNIISDLVRNPSGPCARRIERIDPGDLCTSIIVAAELRYGCAKKGSAKLLNRVESVLAFVPVLPLDIPADCEY
GGIRAELEAAGQTIGMNDLLIAAHAYTLKATLVTNNTREFMRIRGLKVENWLEDGT

Download         Length: 411 bp

Antitoxin


Download         Length: 91 a.a.        Molecular weight: 10414.01 Da        Isoelectric Point: 4.5749

>AT285463 WP_058988176.1 NZ_LN606600:2336230-2336502 [Acetobacter senegalensis]
MPVPEVTPRPREVKLFRNNRSQAVRIPVEFEMPGDRVLIRRDGDKLVLEPVKTPSTLKELLMAWREEPQLAPEDDFPDIQ
DVAARPEDIL

Download         Length: 273 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A5B9GMW7

Antitoxin

Source ID Structure

References