285462

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) BrnTA/BrnT-BrnA
Location 1754737..1755292 Replicon chromosome
Accession NZ_LN606600
Organism Acetobacter senegalensis strain 108B

Toxin (Protein)


Gene name brnT Uniprot ID A0A0U5EVZ0
Locus tag ASN_RS07910 Protein ID WP_058987833.1
Coordinates 1755029..1755292 (-) Length 88 a.a.

Antitoxin (Protein)


Gene name brnA Uniprot ID -
Locus tag ASN_RS07905 Protein ID WP_197603358.1
Coordinates 1754737..1755021 (-) Length 95 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
ASN_RS07875 1750004..1750441 + 438 WP_058987826.1 hypothetical protein -
ASN_RS07880 1750441..1750944 + 504 WP_058987827.1 hypothetical protein -
ASN_RS19615 1751072..1751383 - 312 WP_157765149.1 hypothetical protein -
ASN_RS07885 1751461..1752168 + 708 WP_058987828.1 hypothetical protein -
ASN_RS07890 1752201..1753373 + 1173 WP_058987829.1 hypothetical protein -
ASN_RS07900 1754025..1754549 - 525 WP_058987831.1 hypothetical protein -
ASN_RS07905 1754737..1755021 - 285 WP_197603358.1 BrnA antitoxin family protein Antitoxin
ASN_RS07910 1755029..1755292 - 264 WP_058987833.1 BrnT family toxin Toxin
ASN_RS07915 1755374..1756003 - 630 WP_058987834.1 toxin-antitoxin system HicB family antitoxin -
ASN_RS07925 1756327..1756656 + 330 WP_157765150.1 hypothetical protein -
ASN_RS07930 1756653..1757486 + 834 WP_058987837.1 antA/AntB antirepressor family protein -
ASN_RS07935 1757531..1757716 + 186 WP_058987838.1 hypothetical protein -
ASN_RS07945 1758468..1759727 - 1260 WP_058987840.1 Y-family DNA polymerase -
ASN_RS07950 1759724..1760104 - 381 WP_058987841.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 1721511..1784755 63244


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Ribonuclease toxin, BrnT, of type II toxin-antitoxin system

(5-79)

Antitoxin

BrnA antitoxin of type II toxin-antitoxin system

(19-90)


Sequences

Toxin        


Download         Length: 88 a.a.        Molecular weight: 9988.51 Da        Isoelectric Point: 10.1483

>T285462 WP_058987833.1 NZ_LN606600:c1755292-1755029 [Acetobacter senegalensis]
MRYDWDETKRQSNIAKHGVDFVAADGFEWDVAFVMTSQSANEPRLVAIAPINLRLHVLVFSIETRIVRIISLRKANKREA
KLYAAQT

Download         Length: 264 bp

Antitoxin


Download         Length: 95 a.a.        Molecular weight: 10444.80 Da        Isoelectric Point: 5.1708

>AT285462 WP_197603358.1 NZ_LN606600:c1755021-1754737 [Acetobacter senegalensis]
MPTDEEDARINQGIALDADNPELTERDFRRAVPASVIVPDLASQRRVRGPQKAPTKTLVSMRLDPDLLERLKADGPGWQS
RANDILREAVGLSR

Download         Length: 285 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A0U5EVZ0

Antitoxin

Source ID Structure

References