Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | V | Classification (family/domain) | ghoTS/ghoT-GhoS |
Location | 4295776..4296273 | Replicon | chromosome |
Accession | NZ_LM995446 | ||
Organism | Escherichia coli strain K-12 substr. RV308 |
Toxin (Protein)
Gene name | ghoT | Uniprot ID | L4JJG6 |
Locus tag | ECRV308_RS21175 | Protein ID | WP_001173343.1 |
Coordinates | 4296100..4296273 (+) | Length | 58 a.a. |
Antitoxin (Protein)
Gene name | ghoS | Uniprot ID | L4JK92 |
Locus tag | ECRV308_RS21170 | Protein ID | WP_000398619.1 |
Coordinates | 4295776..4296072 (+) | Length | 99 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
ECRV308_RS21150 | 4292507..4293226 | - | 720 | WP_000611288.1 | two-component system response regulator DcuR | - |
ECRV308_RS21155 | 4293223..4294854 | - | 1632 | WP_001216477.1 | sensor histidine kinase | - |
ECRV308_RS21160 | 4295035..4295265 | + | 231 | WP_000371704.1 | (4Fe-4S)-binding protein | - |
ECRV308_RS21165 | 4295277..4295549 | + | 273 | WP_000405651.1 | N-acetyltransferase | - |
ECRV308_RS21170 | 4295776..4296072 | + | 297 | WP_000398619.1 | type V toxin-antitoxin system endoribonuclease antitoxin GhoS | Antitoxin |
ECRV308_RS21175 | 4296100..4296273 | + | 174 | WP_001173343.1 | type V toxin-antitoxin system toxin GhoT | Toxin |
ECRV308_RS21180 | 4296392..4297909 | - | 1518 | WP_001295074.1 | lysine--tRNA ligase | - |
ECRV308_RS21185 | 4298146..4299603 | - | 1458 | WP_000856829.1 | dipeptide/tripeptide permease DtpC | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Structures
Toxin
Source | ID | Structure |
---|---|---|
AlphaFold DB | A0A7U9QI41 |
Antitoxin
Source | ID | Structure |
---|---|---|
AlphaFold DB | A0A7U9QBH6 |