Detailed information of TA system TA285370

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): mazEF/PemK-MazE
• Location: 13494..14035
• Replicon: plasmid pXOCgx01
• Accession: NZ_KR071788
• Organism: Xanthomonas oryzae pv. oryzicola strain GX01

Toxin (Protein)

• Gene name: mazF
• Uniprot ID: -
• Locus tag: XOCgx_RS22885
• Protein ID: WP_193566048.1
• Coordinates: 13494..13820 (-)
• Length: 109 a.a.

Antitoxin (Protein)

• Gene name: mazE
• Uniprot ID: -
• Locus tag: XOCgx_RS22890
• Protein ID: WP_048485072.1
• Coordinates: 13817..14035 (-)
• Length: 73 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
XOCgx_RS22875	8877..10451	+	1575	WP_150411549.1	type IV secretion system DNA-binding domain-containing protein	-
XOCgx_RS22880	10465..13425	+	2961	WP_048485071.1	conjugative relaxase	-
XOCgx_RS22885	13494..13820	-	327	WP_193566048.1	type II toxin-antitoxin system PemK/MazF family toxin	Toxin
XOCgx_RS22890	13817..14035	-	219	WP_048485072.1	antitoxin MazE family protein	Antitoxin
XOCgx_RS22895	14254..14673	-	420	WP_048485073.1	hypothetical protein	-
XOCgx_RS22900	14799..15707	-	909	WP_048485074.1	lytic transglycosylase domain-containing protein	-
XOCgx_RS22905	15694..16716	-	1023	WP_048485075.1	P-type DNA transfer ATPase VirB11	-
XOCgx_RS22910	16727..17947	-	1221	WP_048485076.1	TrbI/VirB10 family protein	-
XOCgx_RS22915	17949..18731	-	783	WP_075244577.1	P-type conjugative transfer protein VirB9	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Non-Mobilizable plasmid	-	-	1..53206	53206

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• mRNA interferase PemK-like (2-105)

Antitoxin

• Antitoxin MazE-like (5-70)

Sequences

Toxin

Protein

• Length: 109 a.a.
• Molecular weight: 11646.72 Da
• Isoelectric Point: 10.1008

>T285370 WP_193566048.1 NZ_KR071788:c13820-13494 [Xanthomonas oryzae pv. oryzicola]
MMRGDFVTIAMQGDFGKPRPALVIQADQFDAHTTVTVLPVTSTLVAAPLLRITVHPSTDNGLQKPSQVMVDKAMTVKRDK
VGRAFGRVDADALVVIERCLAVFLGIAK

Nucleotide

• Length: 327 bp

Antitoxin

Protein

• Length: 73 a.a.
• Molecular weight: 8360.50 Da
• Isoelectric Point: 6.4486

>AT285370 WP_048485072.1 NZ_KR071788:c14035-13817 [Xanthomonas oryzae pv. oryzicola]
MAHVNSRVQKHRDALRMAGLRPVQIWVPDTRRPDFAAECRRQCRLAAQADMADTDMQRFMDEALADMDGWTE

Nucleotide

• Length: 219 bp