285347

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) EcnAB/-
Location 4450478..4450843 Replicon chromosome
Accession NZ_HG999363
Organism Xanthomonas euroxanthea isolate Xanthomonas euroxanthea CPBF 761 isolated from C. illinoinensis

Toxin (Protein)


Gene name EcnB Uniprot ID A0A0B2CMD0
Locus tag KHN77_RS18880 Protein ID WP_016904515.1
Coordinates 4450478..4450612 (-) Length 45 a.a.

Antitoxin (Protein)


Gene name EcnA Uniprot ID V7Z8F2
Locus tag KHN77_RS18885 Protein ID WP_006451340.1
Coordinates 4450691..4450843 (-) Length 51 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
KHN77_RS18860 (XCY_003773) 4445531..4447225 - 1695 WP_180497048.1 M28 family metallopeptidase -
KHN77_RS18865 (XCY_003774) 4447544..4448488 - 945 WP_119129805.1 MBL fold metallo-hydrolase -
KHN77_RS18870 (XCY_003775) 4448546..4449835 - 1290 WP_119129806.1 tryptophan--tRNA ligase -
KHN77_RS18875 (XCY_003776) 4450029..4450238 - 210 WP_016904514.1 CsbD family protein -
KHN77_RS18880 (XCY_003777) 4450478..4450612 - 135 WP_016904515.1 entericidin A/B family lipoprotein Toxin
KHN77_RS18885 (XCY_003778) 4450691..4450843 - 153 WP_006451340.1 entericidin A/B family lipoprotein Antitoxin
KHN77_RS18890 (XCY_003779) 4450953..4451876 - 924 WP_119129987.1 arginase -
KHN77_RS18895 (XCY_003780) 4452346..4452798 + 453 WP_104649943.1 roadblock/LC7 domain-containing protein -
KHN77_RS18900 (XCY_003781) 4452862..4453221 + 360 WP_119129807.1 roadblock/LC7 domain-containing protein -
KHN77_RS18905 (XCY_003782) 4453316..4454233 + 918 WP_119129808.1 hypothetical protein -
KHN77_RS18910 (XCY_003783) 4454230..4454772 + 543 WP_016904520.1 GTPase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Entericidin A/B

(23-42)

Antitoxin

Entericidin A/B

(23-42)


Sequences

Toxin        


Download         Length: 45 a.a.        Molecular weight: 4443.26 Da        Isoelectric Point: 9.3487

>T285347 WP_016904515.1 NZ_HG999363:c4450612-4450478 [Xanthomonas euroxanthea]
MKRAIVLLVLSVLSVGMLSGCNTVAGAGKDVQGAGEKVEDAARK

Download         Length: 135 bp

Antitoxin


Download         Length: 51 a.a.        Molecular weight: 5168.11 Da        Isoelectric Point: 8.2782

>AT285347 WP_006451340.1 NZ_HG999363:c4450843-4450691 [Xanthomonas euroxanthea]
MKRLLTLMVLGLFSAGVMTGCNTMAGAGKDMQGAGEKVEKKADNCSDGKC

Download         Length: 153 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A0B2CMD0

Antitoxin

Source ID Structure
AlphaFold DB A0A2N7V051

References