Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | PP_4151-4152/excise(antitoxin) |
| Location | 1688677..1689716 | Replicon | chromosome |
| Accession | NZ_HG995459 | ||
| Organism | Pseudomonas sp. PP3 | ||
Toxin (Protein)
| Gene name | PP_4152 | Uniprot ID | - |
| Locus tag | KHO07_RS07855 | Protein ID | WP_212626864.1 |
| Coordinates | 1688677..1689252 (-) | Length | 192 a.a. |
Antitoxin (Protein)
| Gene name | PP_4151 | Uniprot ID | - |
| Locus tag | KHO07_RS07860 | Protein ID | WP_150734860.1 |
| Coordinates | 1689249..1689716 (-) | Length | 156 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| KHO07_RS07825 | 1683794..1684663 | + | 870 | WP_212626858.1 | alpha-D-ribose 1-methylphosphonate 5-phosphate C-P-lyase PhnJ | - |
| KHO07_RS07830 | 1684660..1685466 | + | 807 | WP_212626859.1 | phosphonate C-P lyase system protein PhnK | - |
| KHO07_RS07835 | 1685495..1686214 | + | 720 | WP_212626860.1 | phosphonate C-P lyase system protein PhnL | - |
| KHO07_RS07840 | 1686204..1687349 | + | 1146 | WP_212626861.1 | alpha-D-ribose 1-methylphosphonate 5-triphosphate diphosphatase | - |
| KHO07_RS07845 | 1687349..1687918 | + | 570 | WP_212626862.1 | phosphonate metabolism protein/1,5-bisphosphokinase (PRPP-forming) PhnN | - |
| KHO07_RS07850 | 1687909..1688658 | + | 750 | WP_212626863.1 | phosphonate metabolism protein PhnP | - |
| KHO07_RS07855 | 1688677..1689252 | - | 576 | WP_212626864.1 | PIN domain-containing protein | Toxin |
| KHO07_RS07860 | 1689249..1689716 | - | 468 | WP_150734860.1 | helix-turn-helix domain-containing protein | Antitoxin |
| KHO07_RS07865 | 1689800..1690687 | - | 888 | WP_212627596.1 | LysR family transcriptional regulator | - |
| KHO07_RS07870 | 1690868..1691080 | + | 213 | WP_212626865.1 | type II toxin-antitoxin system HicA family toxin | - |
| KHO07_RS07875 | 1691080..1691484 | + | 405 | WP_075948492.1 | type II toxin-antitoxin system HicB family antitoxin | - |
| KHO07_RS07880 | 1691576..1692781 | - | 1206 | WP_212626866.1 | MFS transporter | - |
| KHO07_RS07885 | 1693104..1694099 | - | 996 | WP_150734856.1 | sulfate ABC transporter substrate-binding protein | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 192 a.a. Molecular weight: 21672.96 Da Isoelectric Point: 6.0980
>T285339 WP_212626864.1 NZ_HG995459:c1689252-1688677 [Pseudomonas sp. PP3]
VRHSAFTAVYDACVLYPAPLRDFLIWLALSGRFRAKWSMEIHNEWKRNLLKNRPDLTIEQLNRTSELMDVAVPDACVKGY
EELIAGLTLPDADDRHVLAAAIRCDASVIVTFNRKDFPCSALGVYDIEAQHPDEFVSNLFDLDPAAVVSAAQRQRKQLKM
PPMDISTYLDLMFRQGLVQSAKALNDYRTML
VRHSAFTAVYDACVLYPAPLRDFLIWLALSGRFRAKWSMEIHNEWKRNLLKNRPDLTIEQLNRTSELMDVAVPDACVKGY
EELIAGLTLPDADDRHVLAAAIRCDASVIVTFNRKDFPCSALGVYDIEAQHPDEFVSNLFDLDPAAVVSAAQRQRKQLKM
PPMDISTYLDLMFRQGLVQSAKALNDYRTML
Download Length: 576 bp
Antitoxin
Download Length: 156 a.a. Molecular weight: 17287.84 Da Isoelectric Point: 6.7707
>AT285339 WP_150734860.1 NZ_HG995459:c1689716-1689249 [Pseudomonas sp. PP3]
MSTVIHPPIHLPAEHEVQIAKAGQHALAAYLCTQIETQRIQIFDEQNEAHNVELPTSALRLLVDILAELAAGNAVKVVPV
HAELTTQEAADLLNVSRPHLIKLLESGELSYHKTGKHRRVRFADLMDYKTRRNAASEQAMMLLAEQAQALRKGYE
MSTVIHPPIHLPAEHEVQIAKAGQHALAAYLCTQIETQRIQIFDEQNEAHNVELPTSALRLLVDILAELAAGNAVKVVPV
HAELTTQEAADLLNVSRPHLIKLLESGELSYHKTGKHRRVRFADLMDYKTRRNAASEQAMMLLAEQAQALRKGYE
Download Length: 468 bp
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
Structures
Toxin
| Source | ID | Structure |
|---|
Antitoxin
| Source | ID | Structure |
|---|