Detailed information of TA system TA028533

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relBE/-
• Location: 651513..652119
• Replicon: chromosome
• Accession: NC_019729
• Organism: Oscillatoria nigro-viridis PCC 7112

Toxin (Protein)

• Gene name: relE
• Uniprot ID: K9VD39
• Locus tag: OSC7112_RS02895
• Protein ID: WP_015174487.1
• Coordinates: 651513..651875 (-)
• Length: 121 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: K9VBC6
• Locus tag: OSC7112_RS02900
• Protein ID: WP_015174488.1
• Coordinates: 651865..652119 (-)
• Length: 85 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
OSC7112_RS02870	646850..647323	-	474	WP_015174481.1	PAM68 family protein	-
OSC7112_RS02875	647419..647688	-	270	WP_015174482.1	30S ribosomal protein S15	-
OSC7112_RS02880	647969..648178	-	210	WP_015174483.1	hypothetical protein	-
OSC7112_RS02885	648184..648552	-	369	WP_015174484.1	GIY-YIG nuclease family protein	-
OSC7112_RS02890	650871..651494	-	624	WP_015174486.1	Holliday junction branch migration protein RuvA	-
OSC7112_RS02895	651513..651875	-	363	WP_015174487.1	hypothetical protein	Toxin
OSC7112_RS02900	651865..652119	-	255	WP_015174488.1	hypothetical protein	Antitoxin
OSC7112_RS02905	652186..654834	-	2649	WP_015174489.1	AAA-like domain-containing protein	-
OSC7112_RS02910	655782..655991	+	210	WP_015174490.1	hypothetical protein	-
OSC7112_RS02915	656267..656839	+	573	WP_015174491.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Antitoxin

No domain identified.

Sequences

Toxin

Protein

• Length: 121 a.a.
• Molecular weight: 13848.90 Da
• Isoelectric Point: 6.3958

>T28533 WP_015174487.1 NC_019729:c651875-651513 [Oscillatoria nigro-viridis PCC 7112]
MLNESELVQIDLTPQYKRNLRELSKRFRQIRLDTGLVIEQLQAGNFIGDRIPGMGEDYIILKVRVKNSNIQKGKSAGYRM
IYQVESPVSVLLLTIYSKSDRTDISLNEIRSIIAEFDENE

Nucleotide

• Length: 363 bp

>T28533 NC_019729:c651875-651513 [Oscillatoria nigro-viridis PCC 7112]
ATGTTGAATGAATCCGAGCTCGTTCAGATCGATTTAACGCCTCAGTATAAGCGAAATTTGCGTGAATTATCCAAACGATT
TCGCCAAATCCGGCTAGATACTGGGCTAGTAATTGAGCAACTACAGGCTGGCAATTTTATTGGCGATCGCATTCCCGGAA
TGGGCGAAGATTATATCATCTTAAAAGTCCGGGTGAAAAACAGCAACATCCAAAAAGGAAAAAGTGCAGGATATCGCATG
ATTTATCAAGTCGAATCGCCCGTCAGCGTACTTTTGTTAACCATTTACTCAAAATCAGATCGAACAGATATCAGCCTCAA
CGAAATCCGCAGCATCATCGCCGAGTTTGACGAAAACGAATAG

Antitoxin

Protein

• Length: 85 a.a.
• Molecular weight: 9252.51 Da
• Isoelectric Point: 4.0265

>AT28533 WP_015174488.1 NC_019729:c652119-651865 [Oscillatoria nigro-viridis PCC 7112]
MKAFEVTGTIDEKGQLILDRPLTLDTPGPVRIIVLLPEPTDEGEDDPDDTPVAEIKASLKRALQEAKTGQRIPLSQMWEG
IDVE

Nucleotide

• Length: 255 bp

>AT28533 NC_019729:c652119-651865 [Oscillatoria nigro-viridis PCC 7112]
ATGAAAGCCTTTGAAGTCACAGGAACGATCGACGAAAAAGGTCAATTAATTCTCGATCGACCTTTAACACTAGACACTCC
GGGCCCCGTGCGAATTATCGTCCTTCTTCCCGAACCTACAGATGAAGGTGAAGACGACCCCGACGATACTCCAGTTGCAG
AAATAAAAGCCAGTCTCAAAAGAGCGTTGCAGGAAGCTAAAACTGGGCAGCGAATACCTCTTTCTCAAATGTGGGAGGGC
ATCGATGTTGAATGA

Structures

Toxin

• AlphaFold DB: K9VD39

Antitoxin

• AlphaFold DB: K9VBC6