Detailed information of TA system TA028530

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relBE/-
• Location: 988143..988662
• Replicon: chromosome
• Accession: NC_019702
• Organism: Synechococcus sp. PCC 7502

Toxin (Protein)

• Gene name: relE
• Uniprot ID: K9ST21
• Locus tag: SYN7502_RS04815
• Protein ID: WP_015167755.1
• Coordinates: 988375..988662 (+)
• Length: 96 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: K9SSH3
• Locus tag: SYN7502_RS04810
• Protein ID: WP_015167754.1
• Coordinates: 988143..988382 (+)
• Length: 80 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
SYN7502_RS04805	984637..988131	+	3495	WP_041429241.1	N-6 DNA methylase	-
SYN7502_RS04810	988143..988382	+	240	WP_015167754.1	hypothetical protein	Antitoxin
SYN7502_RS04815	988375..988662	+	288	WP_015167755.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
SYN7502_RS04820	988754..988960	+	207	WP_041429914.1	hypothetical protein	-
SYN7502_RS04825	989571..990665	+	1095	WP_015167757.1	S-methyl-5-thioribose-1-phosphate isomerase	-
SYN7502_RS04830	990693..991121	-	429	WP_015167758.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (7-92)

Antitoxin

No domain identified.

Sequences

Toxin

Protein

• Length: 96 a.a.
• Molecular weight: 10800.61 Da
• Isoelectric Point: 10.5397

>T28530 WP_015167755.1 NC_019702:988375-988662 [Synechococcus sp. PCC 7502]
MTNQIHVEASPTFLKNIRTLRKKYPRIQNDMQSVIQQLEQGKLLGDQISGVGYPVFKLRVKNSDIQKGKSGGYRLIYYVK
TATGIVLLTVYPKSE

Nucleotide

• Length: 288 bp

>T28530 NC_019702:988375-988662 [Synechococcus sp. PCC 7502]
ATGACTAACCAAATCCACGTTGAAGCCTCACCAACATTTCTAAAAAATATCCGCACACTTCGCAAAAAATATCCACGCAT
TCAGAATGATATGCAATCAGTCATTCAACAACTAGAGCAAGGAAAGTTATTAGGCGATCAAATATCAGGTGTTGGTTATC
CTGTCTTCAAACTGAGAGTTAAAAATAGTGACATTCAAAAAGGAAAAAGTGGCGGCTATCGTCTAATTTATTATGTCAAA
ACAGCGACAGGAATCGTTTTGCTGACCGTTTACCCCAAATCTGAATAA

Antitoxin

Protein

• Length: 80 a.a.
• Molecular weight: 9100.31 Da
• Isoelectric Point: 3.9847

>AT28530 WP_015167754.1 NC_019702:988143-988382 [Synechococcus sp. PCC 7502]
MQAVKVMASINEKGQLTLDYPLELKTNSRVEVIILVSEPEEPEEISKQEIIADFRQAWHEAMTEQTIPVSAMWEQLEND

Nucleotide

• Length: 240 bp

>AT28530 NC_019702:988143-988382 [Synechococcus sp. PCC 7502]
ATGCAAGCAGTTAAAGTAATGGCAAGCATCAACGAAAAAGGTCAACTCACCTTAGATTATCCCCTTGAGCTAAAGACAAA
TAGCCGAGTTGAAGTAATCATTCTTGTGTCTGAACCCGAAGAACCCGAAGAAATATCTAAACAAGAAATCATCGCTGACT
TTCGACAAGCTTGGCACGAAGCAATGACAGAGCAAACCATTCCTGTATCAGCAATGTGGGAGCAACTAGAAAATGACTAA

Structures

Toxin

• AlphaFold DB: K9ST21

Antitoxin

• AlphaFold DB: K9SSH3