Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2249033..2249301 Replicon chromosome
Accession NZ_HG994850
Organism Escherichia coli isolate 127

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2249161..2249263 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2249033..2249301 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LLO83_RS10510 2245585..2246247 - 663 WP_000944256.1 exodeoxyribonuclease X -
LLO83_RS10515 2246271..2246927 - 657 WP_000011644.1 carbon-nitrogen hydrolase family protein YobB -
LLO83_RS10520 2247030..2247260 - 231 WP_000916763.1 DNA polymerase III subunit theta -
LLO83_RS10525 2247399..2247773 + 375 WP_000168747.1 CopC domain-containing protein YobA -
LLO83_RS10530 2247777..2248649 + 873 WP_000879311.1 copper homeostasis membrane protein CopD -
LLO83_RS10535 2248662..2249003 + 342 WP_000984819.1 YebY family protein -
- 2249033..2249301 - 269 - - Antitoxin
- 2249161..2249263 + 103 - - Toxin
LLO83_RS10540 2249398..2250054 + 657 WP_000812743.1 protein-serine/threonine phosphatase -
LLO83_RS10545 2250055..2250246 - 192 WP_001296140.1 YebW family protein -
LLO83_RS10550 2250351..2250587 - 237 WP_001295499.1 YebV family protein -
LLO83_RS10555 2250705..2252144 - 1440 WP_001298454.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T285290 NZ_HG994850:2249161-2249263 [Escherichia coli]
GCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 269 bp

>AT285290 NZ_HG994850:c2249301-2249033 [Escherichia coli]
AAAGTCAGCGAAGGGAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCTCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References