Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) ataRT/DUF1778(antitoxin)
Location 2017395..2018158 Replicon chromosome
Accession NZ_HG992758
Organism Vibrio sp. B1FLJ16 isolate B1REV17

Toxin (Protein)


Gene name ataT Uniprot ID A0A919BFZ0
Locus tag KHN94_RS09160 Protein ID WP_023584043.1
Coordinates 2017652..2018158 (+) Length 169 a.a.

Antitoxin (Protein)


Gene name ataR Uniprot ID -
Locus tag KHN94_RS09155 Protein ID WP_000212004.1
Coordinates 2017395..2017661 (+) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
KHN94_RS09145 (ACOMICROBIO_EPCKBFOG_01869) 2012744..2013853 - 1110 WP_182029135.1 hypothetical protein -
KHN94_RS09150 (ACOMICROBIO_LOCUS1317) 2013850..2016579 - 2730 WP_182029137.1 DEAD/DEAH box helicase -
KHN94_RS09155 (ACOMICROBIO_LOCUS1318) 2017395..2017661 + 267 WP_000212004.1 DUF1778 domain-containing protein Antitoxin
KHN94_RS09160 (ACOMICROBIO_LOCUS1319) 2017652..2018158 + 507 WP_023584043.1 GNAT family N-acetyltransferase Toxin
KHN94_RS09165 (ACOMICROBIO_EPCKBFOG_01873) 2018199..2018585 - 387 WP_000180225.1 TraA family conjugative transfer protein -
KHN94_RS09170 (ACOMICROBIO_EPCKBFOG_01874) 2018582..2019154 - 573 WP_001944091.1 type IV conjugative transfer system lipoprotein TraV -
KHN94_RS09175 (ACOMICROBIO_EPCKBFOG_01875) 2019229..2020518 - 1290 WP_182029139.1 TraB/VirB10 family protein -
KHN94_RS09180 (ACOMICROBIO_EPCKBFOG_01876) 2020521..2021417 - 897 WP_182029237.1 type-F conjugative transfer system secretin TraK -
KHN94_RS09185 (ACOMICROBIO_EPCKBFOG_01877) 2021401..2022027 - 627 WP_000667170.1 TraE/TraK family type IV conjugative transfer system protein -
KHN94_RS09190 (ACOMICROBIO_EPCKBFOG_01878) 2022024..2022305 - 282 WP_000433891.1 type IV conjugative transfer system protein TraL -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Integrative and Conjugative Element - - 1952409..2046621 94212


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

GNAT domain

(42-146)

Antitoxin

Vibrio phage ICP1, Orf50

(8-83)


Sequences

Toxin        


Download         Length: 169 a.a.        Molecular weight: 18278.00 Da        Isoelectric Point: 7.2132

>T285282 WP_023584043.1 NZ_HG992758:2017652-2018158 [Vibrio sp. B1FLJ16]
MGISAPTLLTDEHQLNAFQCGIEELDTWLRKQALKSQKRGTARVYVVNDTDAHQVVGYYAIAMGSVSREQAFSSLRRNSP
DPIPMVILARLGVDNAYQGQGIAAGLLKDCIIRSVQAMNAVGGAGILVHAIDGSAQTFYKKFGFKESTFDPLVLMARICD
IEKSLSID

Download         Length: 507 bp

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 9956.48 Da        Isoelectric Point: 5.8580

>AT285282 WP_000212004.1 NZ_HG992758:2017395-2017661 [Vibrio sp. B1FLJ16]
MATKTAPINMRVLPSVRDIIDAAASLKKVDRTVFIQQAALNEAHSILAEQRDFVLEAKAFEAFDNELRAEPQTLEGMKDL
FKRKAPWE

Download         Length: 267 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References