Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/YafN(antitoxin)
Location 1824116..1824681 Replicon chromosome
Accession NZ_HG992758
Organism Vibrio sp. B1FLJ16 isolate B1REV17

Toxin (Protein)


Gene name relE Uniprot ID A0A7X8U0A9
Locus tag KHN94_RS08305 Protein ID WP_029865673.1
Coordinates 1824116..1824403 (-) Length 96 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag KHN94_RS08310 Protein ID WP_182032589.1
Coordinates 1824400..1824681 (-) Length 94 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
KHN94_RS08285 (ACOMICROBIO_LOCUS1208) 1820488..1821180 + 693 WP_182011762.1 NAD(P)H-binding protein -
KHN94_RS08290 (ACOMICROBIO_LOCUS1209) 1821370..1822749 + 1380 WP_182032573.1 L-cystine transporter -
KHN94_RS08295 (ACOMICROBIO_EPCKBFOG_01699) 1823109..1823462 - 354 WP_182011760.1 DUF1428 domain-containing protein -
KHN94_RS08300 1823586..1823717 + 132 Protein_1609 IS110 family transposase -
KHN94_RS08305 (ACOMICROBIO_EPCKBFOG_01700) 1824116..1824403 - 288 WP_029865673.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
KHN94_RS08310 (ACOMICROBIO_LOCUS1210) 1824400..1824681 - 282 WP_182032589.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
KHN94_RS08315 (ACOMICROBIO_LOCUS1211) 1824835..1825860 + 1026 WP_211910496.1 IS110 family transposase -
KHN94_RS08320 (ACOMICROBIO_LOCUS1212) 1826216..1827220 - 1005 WP_182028970.1 LD-carboxypeptidase -
KHN94_RS08325 (ACOMICROBIO_LOCUS1213) 1827477..1828439 + 963 WP_182028972.1 integron integrase -
KHN94_RS08330 (ACOMICROBIO_EPCKBFOG_01705) 1828498..1828971 - 474 WP_182008310.1 DUF2947 domain-containing protein -
KHN94_RS08335 (ACOMICROBIO_EPCKBFOG_01706) 1828985..1829572 - 588 WP_182008311.1 HD domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- flank IS/Tn - - 1824835..1825860 1025


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(3-88)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(9-74)


Sequences

Toxin        


Download         Length: 96 a.a.        Molecular weight: 10993.65 Da        Isoelectric Point: 5.1098

>T285281 WP_029865673.1 NZ_HG992758:c1824403-1824116 [Vibrio sp. B1FLJ16]
MKVVWSPLALQKLGDAAEFISLDNPSAAEKWVNEVFDKTELLGSMPEMGRFVPEMPHTNYREIIFGHYRIIYSLSHEIRV
LTVRNCRQILSEDDV

Download         Length: 288 bp

Antitoxin


Download         Length: 94 a.a.        Molecular weight: 10335.85 Da        Isoelectric Point: 6.4691

>AT285281 WP_182032589.1 NZ_HG992758:c1824681-1824400 [Vibrio sp. B1FLJ16]
MSRIHFDQDIQPLSEFRAGVASYIKQINETRRPLVITQHGKGVAVVLDVAEYEAMQEKIELLEEMRTAEAQLASGLGVSN
ADARAQVLGRIKK

Download         Length: 282 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A7X8U0A9

Antitoxin

Source ID Structure

References