Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) mazEF/PRK09907-MazE
Location 525463..526049 Replicon chromosome
Accession NZ_HG992743
Organism Vibrio sp. B1ASS3

Toxin (Protein)


Gene name mazF Uniprot ID -
Locus tag KJB05_RS20885 Protein ID WP_208446377.1
Coordinates 525720..526049 (+) Length 110 a.a.

Antitoxin (Protein)


Gene name mazE Uniprot ID -
Locus tag KJB05_RS20880 Protein ID WP_208446378.1
Coordinates 525463..525720 (+) Length 86 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
KJB05_RS20850 (ACOMICROBIO_LOCUS4107) 520609..521262 - 654 WP_208446451.1 DsbA family oxidoreductase -
KJB05_RS20855 (ACOMICROBIO_LOCUS4108) 521457..522620 + 1164 WP_208446452.1 MerR family transcriptional regulator -
KJB05_RS20860 (ACOMICROBIO_NCLOACGD_04244) 522628..523078 + 451 Protein_497 GNAT family N-acetyltransferase -
KJB05_RS28780 523357..523982 - 626 Protein_498 IS110 family transposase -
KJB05_RS20875 (ACOMICROBIO_NCLOACGD_04247) 523986..524552 + 567 Protein_499 hypothetical protein -
KJB05_RS20880 (ACOMICROBIO_LOCUS4111) 525463..525720 + 258 WP_208446378.1 AbrB/MazE/SpoVT family DNA-binding domain-containing protein Antitoxin
KJB05_RS20885 (ACOMICROBIO_LOCUS4112) 525720..526049 + 330 WP_208446377.1 type II toxin-antitoxin system PemK/MazF family toxin Toxin
KJB05_RS20890 (ACOMICROBIO_LOCUS4113) 526117..526806 + 690 WP_208446376.1 ParA family protein -
KJB05_RS28785 (ACOMICROBIO_NCLOACGD_04251) 526816..527424 + 609 WP_244142984.1 hypothetical protein -
KJB05_RS20900 527835..528101 + 267 Protein_504 IS91 family transposase -
KJB05_RS20910 (ACOMICROBIO_LOCUS4114) 528458..529210 - 753 WP_208446375.1 hypothetical protein -
KJB05_RS20915 (ACOMICROBIO_LOCUS4115) 529511..530719 - 1209 WP_208446374.1 IS256 family transposase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- flank IS/Tn - - 523357..523641 284


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase PemK-like

(6-102)

Antitoxin

SpoVT-AbrB domain

(8-50)


Sequences

Toxin        


Download         Length: 110 a.a.        Molecular weight: 12214.32 Da        Isoelectric Point: 10.2893

>T285275 WP_208446377.1 NZ_HG992743:525720-526049 [Vibrio sp. B1ASS3]
MYIPDKGDIVTLDFDSSAGKEIMKRRPAFVISRKMFNEHTGFAVVAPITSTIRGMKLEVVLPESLSTQGAVLIHQVKSLD
FSNRQIRFVEKAPKHITEKVSELTKVIIS

Download         Length: 330 bp

Antitoxin


Download         Length: 86 a.a.        Molecular weight: 9192.60 Da        Isoelectric Point: 4.5488

>AT285275 WP_208446378.1 NZ_HG992743:525463-525720 [Vibrio sp. B1ASS3]
MTAVTIRQSGGANIVSIPKAIVKTLSLHTGSKLELSIQDNNIVLSPIEEELTLESVLAGSPKTCFAITEEDKEWMNDKPV
GKEII

Download         Length: 258 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References